科研喵使用AI读文献,祝你效率百倍,访问LabCat.com.cn下载。全新研究揭秘大型B细胞淋巴瘤的秘密!最新发表在《癌症细胞》杂志上的研究发现,通过单核多组学分析,232个肿瘤和对照活检样本揭示了大型B细胞淋巴瘤(LBCL)中不同的微环境原型(LymphoMAPs)。这些微环境与T细胞的稀缺程度、癌细胞相关成纤维细胞和肿瘤相关巨噬细胞的高频率相关,并与不同的临床结果紧密相连,特别是在CD19嵌合抗原受体(CAR)T细胞疗法后。这一发现为淋巴瘤的精准治疗提供了新见解,值得期待!
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