科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。 本期关注发表在《Pharmacological research》(IF: 9.1)上的重要研究《The potential of CDK4/6 inhibitors in advancing the treatment of cutaneous melanoma》。这项研究揭示了CDK4/6抑制剂在皮肤黑色素瘤治疗中的巨大潜力。研究指出，CDK4/6抑制剂不仅能诱导肿瘤衰老，还能调节肿瘤微环境并增强免疫反应。尤其重要的是，这些药物与现有疗法（如MAPK抑制剂和免疫检查点抑制剂）联合使用，可能有效克服治疗抵抗，提高治疗效果，为晚期黑色素瘤患者提供新的治疗策略。这一发现为黑色素瘤治疗开辟了新方向，有望改善患者预后。
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