科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。 欢迎收听今天的医学前沿！我们关注发表在Journal of nanobiotechnology(影响因子10.6)上的重要研究："Programmable metal-based immuno-photocatalytic nanoparticles for precision activation of anti-tumor immunity."这项突破性研究开发了可编程金属基免疫光催化纳米颗粒，能够通过整合光疗和免疫调节，时空精准激活抗肿瘤免疫反应。这些纳米颗粒不仅能刺激免疫原性细胞死亡并释放肿瘤抗原，还能共同递送免疫检查点抑制剂和佐剂，重塑肿瘤微环境。临床前模型显示，它们能有效抑制肿瘤、激活免疫并预防转移，且全身毒性极低。这项技术为克服免疫抵抗肿瘤的治疗障碍提供了新思路，有望实现高度个性化的癌症免疫治疗！
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