科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在Neurology(影响因子7.7)的重要研究："Resective Surgery for Drug-Resistant Epilepsy in Patients With Tuberous Sclerosis Complex: A Prospective Nationwide Multicenter Cohort Study"。这项中国21个中心的前瞻性队列研究纳入200名患者，发现切除手术对结节性硬化症相关药物难治性癫痫患者效果显著——手术组1年无癫痫发作率高达77%，而药物组仅13%。手术后患者智商和生活质量显著改善，且安全性不劣于药物治疗。MRI上突出的结节是术后良好预后的预测因子，为临床决策提供了重要依据。
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