科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。 本期关注最新发表在《Cancer》(影响因子6.1)上的重要研究"A tour of leukemia progress in 2025, viewed through the MD Anderson leukemia research lens"。这项回顾性研究揭示了白血病治疗的革命性进展，过去20年靶向治疗彻底改变了治疗格局。从blinatumomab等抗体药物到BCR::ABL1抑制剂等小分子靶向药，不仅提高了患者生存率，还减少了对传统化疗的依赖。研究显示，更多白血病类型现被归类为"有利型"，包括慢性淋巴细胞白血病和特定急性淋巴细胞白血病亚型。然而，对于TP53突变等高风险患者群体，仍需开发更有效的治疗方案。这项进展为临床医生提供了宝贵的治疗参考，也为未来研究指明了方向。
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