【科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载】 欢迎收听今日医学前沿！最新发表在《Cancer treatment reviews》(影响因子9.6)上的研究"Precision oncology in gastric cancer: Shaping the future of personalized treatment"为胃癌治疗带来新希望。胃癌作为全球第三大癌症死因，因晚期诊断和高度异质性而预后极差。研究团队回顾了近年来开发的预临床模型，包括患者来源异种移植物、类器官和基因工程小鼠模型，这些工具有助于阐明疾病机制和药物测试。文章还强调了免疫疗法、抗体药物偶联物和合成致死等创新策略，有望克服当前治疗的耐药机制。这些突破性进展为胃癌患者带来了更精准、更有效的个性化治疗选择，有望显著改善临床预后。
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