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科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注的是发表在影响因子5.1的British Journal of Haematology上的研究"Chronic myelomonocytic leukaemia"。这项重要研究揭示了CMML作为一种独特的混合性血液肿瘤，其特征是克隆性单核细胞增多，超过90%患者存在骨髓肿瘤相关体细胞突变。研究强调当前CMML治疗多为姑息性质，而异基因造血干细胞移植是唯一可能治愈的手段。文章详细介绍了BLAST和BLAST-分子风险模型等新预后工具如何帮助确定最佳移植时机，为临床医生提供重要决策依据。这项研究对改善CMML患者的治疗选择和预后评估具有重要意义。
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