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Aaron Boster

👤 Person
887 total appearances

Appearances Over Time

Podcast Appearances

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And if they saw like the Mongol hordes, they would light the bonfire.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And then miles away, a guy would see the bonfire and he would light his bonfire.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And you could communicate up and down the Great Wall of China wicked fast.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

That's the way like a wire works when it's not damaged.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

That's the way the neuron works when it's not damaged.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

When it's damaged and you have to put in all these sodium channels, now you can't propagate a message really quickly.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And so if I use the Great Wall of China, the bonfire is out.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

There's no bonfire.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

So what the guy does, he jumps on a horse and as fast as he can, he rides down the Great Wall, which is way the heck slower.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And it still gets the message there, but it doesn't work as fast.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Now, let's go back to the neuron, the wire.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

That system is extremely heat sensitive.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Those ion channels are extremely heat sensitive.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

So if you heat the human body up, you leach the ions out, and again, you have conduction block.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And when the body cools back down, it works again.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

Now, this drives people with MS crazy because they'll be fine in the beginning of a walk.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And as they walk and their body gets hotter and hotter, they short circuit.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

And sometimes, you know, people they're with will say, what the heck?

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

You were fine, you know, just earlier today.

Ologies with Alie Ward
Neuropathoimmunology (MULTIPLE SCLEROSIS) with Aaron Boster

But it's because of this heat sensitivity phenomenon.