Aaron Boster

And so we talk about an autologous hematopoietic stem cell transplant, and it's a very sexy concept.

I'm going to swap out my bone marrow and then I won't have an autoimmune condition.

So a couple of things.

Number one, it's not a drug, it's a procedure.

Number two, it's a very morbid procedure.

It's a draconian maneuver where you take the person and you make them make stem cells and you put them on ice.

Then you murder them.

You give them lethal doses of chemotherapy and you remove their immune system, like John Travolta, Boy in the Bubble, where they have no immune system and they would succumb to a cold.

But before they die, God forbid, you give them back the immune system, the stem cells.

Now, what's interesting is the stem cells don't help the MS, right?

The stem cells prevent you from dying.

The ablation of the immune system is what helps the MS.

And this has been studied increasingly.

There's huge efforts, gigantic efforts in Italy, gigantic efforts in Canada.

There's ongoing studies in the United States looking at stem cell transplantation, mostly targeting really severe cases of multiple sclerosis.

And it's not prime time, in my opinion.

When I look at some of the most effective medicines to treat MS, they, in some studies, fare as well as stem cell transplantation, sometimes maybe a little less, but the safety profiles are much better.

Yeah.

And so I don't feel like the answer to MS is stem cell transplantation.

I'll also point out two more things that when someone gets a stem cell transplant, it accelerates the brain shrinkage, the brain atrophy because of the intense chemo.