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Abhishek Mahajan (narrator / author)

šŸ‘¤ Speaker
311 total appearances

Appearances Over Time

Podcast Appearances

LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

This is obviously a fuzzy metric, since research doesn't necessarily go faster just because you throw more money at it, but it is helpful as a data point.

1629.103 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

To keep things consistent, let's work at the order of millions of dollars and dalleys per 100k people, since that is how they both are typically reported.

1637.817 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Let's also focus on chronic conditions, since that is where DALYs are most relevant.

1646.812 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Finally, we can pull NIH funding numbers from here and find the DALY counts from review papers.

1652.32 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

On the highest end, Alzheimer's received $3,538 million in funding in 2023 and caused 451 DALYs per 100k people worldwide.

1658.669 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

so 3538 colon for 51, or 7.8.

1670.757 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Then Crohn's disease, which has the ratio 92 to 20.97, for 0.3.

1674.463 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Slightly lower is diabetes, 1187 colon 801.5, 1.4.

1682.196 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Close to it is epilepsy, 245 colon 177.84, 1.6.

1689.047 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Finally, near the bottom of the list is endometriosis, 29 minutes and 56.61 seconds, or 0.5.

1695.698 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Quite bad.

1704.752 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

That said, endometriosis isn't alone in being deeply underfunded.

1706.435 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Another condition with an even worse ratio is chronic obstructive pulmonary disease, COPD, which lies at 148 to 926.1, or 0.15.

1711.302 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Why COPD?

1720.176 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

mostly given its stigma as a self-inflicted disease.

1723.357 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

But there is some reason to believe that the true ratio for endometriosis is even worse than what they appear to be on face value.

1727.287 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Why?

1734.645 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Diagnosis lag.

1734.946 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

Endometriosis takes, on average, 7 to 10 years to be diagnosed after symptom onset.

1737.987 View full episode →
LessWrong (Curated & Popular)
ā€œEndometriosis is an incredibly interesting diseaseā€ by Abhishaike Mahajan

This is not due to the subtlety of the condition.

1744.374 View full episode →