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Alex McColgan

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
22900 total appearances

Appearances Over Time

Podcast Appearances

Astrum Space
What Would Alien Life Look Like?

How on Earth could life emerge?

Astrum Space
What Would Alien Life Look Like?

Well, there is little consensus on the precise way that life actually emerged on Earth, but let's explore the molecules that, without exception, build every single life form on Earth.

Astrum Space
What Would Alien Life Look Like?

Perhaps life offers clues to its own origin.

Astrum Space
What Would Alien Life Look Like?

The key basic building blocks life uses today in no particular order are fatty acids, amino acids, and nucleotides, and all three are believed to have been present on the early Earth, and have even been found on asteroids in our solar system.

Astrum Space
What Would Alien Life Look Like?

The first are fatty acids, and despite having little chemical functionality, they create structure and have an extraordinary function built in.

Astrum Space
What Would Alien Life Look Like?

These long chain molecules make up cell walls of all life on Earth and are believed to have made the first membranes of protocells.

Astrum Space
What Would Alien Life Look Like?

Membranes are barriers and fundamental to create an individual unit.

Astrum Space
What Would Alien Life Look Like?

After all, you can't have a house without walls or a country without borders.

Astrum Space
What Would Alien Life Look Like?

That's not a political statement.

Astrum Space
What Would Alien Life Look Like?

Remarkably, cell-like structures made from fatty acids form spontaneously in water.

Astrum Space
What Would Alien Life Look Like?

As anyone who's failed to make simple mayonnaise will know all too well, oil and water don't like to mix.

Astrum Space
What Would Alien Life Look Like?

These fatty acids, with a water-loving head and a water-hating tail,

Astrum Space
What Would Alien Life Look Like?

will spontaneously arrange to minimize water's contact with the tail and maximize it with the head.

Astrum Space
What Would Alien Life Look Like?

These simple pressures can create a bilayer membrane with a cavity for an early cell to call home.

Astrum Space
What Would Alien Life Look Like?

This is called a liposome.

Astrum Space
What Would Alien Life Look Like?

Unbelievably, these liposomes can also spontaneously divide and speed up chemical reactions by encapsulating and concentrating the molecules in a smaller space.

Astrum Space
What Would Alien Life Look Like?

This is a perfect example of how unexpected life-like behaviours can emerge out of the laws of quantum mechanics.

Astrum Space
What Would Alien Life Look Like?

But won't these crude divisions just go wrong and kill the cell more often than not in hot, salty water?

Astrum Space
What Would Alien Life Look Like?

Well, yes, there's a good chance.

Astrum Space
What Would Alien Life Look Like?

However, the environment isn't a simple system.