Andrew Huberman

And I know we normally look at babies and children and kids in puberty and we think, oh, they're so vital, they're so young.

And yet the way you describe these changes in the epigenome and the way you have framed aging as a disease leads me to ask,

Are periods of immense vitality the same periods when we're aging faster?

Incredible.

Yeah.

This is more of an anecdotal phenomenon.

It is an anecdotal phenomenon, but at this experience of in junior high school, you know, going home for a summer and you come back and then some of the kids, like they grew beards over the summer or they completely matured quickly over the summer.

Do you think there's any reason to believe that rates of entry into and through puberty have can predict overall rates of aging?

Can we say that there's a direct relationship between body size and longevity?

So let's talk about some of the things that people can do.

And I've kind of batched these into categories rather than just diving right into actionable protocols.

So the first one relates to food, blood sugar, insulin.

This is something I hear a lot about that fasting is good for us, but rarely do I hear why it's good for us.

I think understanding the mechanism will allow people to make better choices.

and not simply to just decide whether or not they're going to fast or not fast or how long they're going to fast, I think should be dictated by some understanding of the mechanism.

So why is it that having elevated blood sugar, glucose and insulin ages us more quickly?

And or why is it that having periods of time each day or perhaps longer can extend our lifespan?

Do you ever do longer fasts, like 48 hours or 72 hours or week-long fasts?

We've known for a long time that there are things that we can do to improve our sleep.

And that includes things that we can take, things like magnesium threonate, theanine, chamomile extract, and glycine, along with lesser known things like saffron and valerian root.