Andrew Steele
👤 PersonAppearances Over Time
Podcast Appearances
One of these diseases that are much more likely as you get older, and these diseases too get exponentially more likely as you increase in age, that's something that eventually becomes severe enough to take your life. And so, you know, it's very much the pain, the suffering, all of these things together that we want to try and get rid of.
One of these diseases that are much more likely as you get older, and these diseases too get exponentially more likely as you increase in age, that's something that eventually becomes severe enough to take your life. And so, you know, it's very much the pain, the suffering, all of these things together that we want to try and get rid of.
And actually, it's a really good way of thinking about it, is to think about a lot of modern medicine seeks to treat individual diseases. But even if we had, hypothetically, a complete success treating an individual disease, and let's take the example, imagine that, you know, we cured cancer tomorrow. That would only add about three years to human life expectancy.
And actually, it's a really good way of thinking about it, is to think about a lot of modern medicine seeks to treat individual diseases. But even if we had, hypothetically, a complete success treating an individual disease, and let's take the example, imagine that, you know, we cured cancer tomorrow. That would only add about three years to human life expectancy.
And actually, it's a really good way of thinking about it, is to think about a lot of modern medicine seeks to treat individual diseases. But even if we had, hypothetically, a complete success treating an individual disease, and let's take the example, imagine that, you know, we cured cancer tomorrow. That would only add about three years to human life expectancy.
And that's because, you know, if you avoid getting cancer, you've probably already got a bit of heart disease or diabetes or, you know, dementia starting, you know, waiting in the wings to kill you as you get older. And so that means that it doesn't make you healthier for much longer.
And that's because, you know, if you avoid getting cancer, you've probably already got a bit of heart disease or diabetes or, you know, dementia starting, you know, waiting in the wings to kill you as you get older. And so that means that it doesn't make you healthier for much longer.
And that's because, you know, if you avoid getting cancer, you've probably already got a bit of heart disease or diabetes or, you know, dementia starting, you know, waiting in the wings to kill you as you get older. And so that means that it doesn't make you healthier for much longer.
Whereas by treating the aging process, the thing that causes all of these diseases, we can potentially defer those diseases, maybe even prevent them entirely and create a lot more healthy years for people.
Whereas by treating the aging process, the thing that causes all of these diseases, we can potentially defer those diseases, maybe even prevent them entirely and create a lot more healthy years for people.
Whereas by treating the aging process, the thing that causes all of these diseases, we can potentially defer those diseases, maybe even prevent them entirely and create a lot more healthy years for people.
These are all good ideas, and they're definitely something that I would encourage people to do, but the fact is we can go beyond this with medicine. And I think the best way to explain this is with an example.
These are all good ideas, and they're definitely something that I would encourage people to do, but the fact is we can go beyond this with medicine. And I think the best way to explain this is with an example.
These are all good ideas, and they're definitely something that I would encourage people to do, but the fact is we can go beyond this with medicine. And I think the best way to explain this is with an example.
One of the biological processes behind aging is the accumulation of aged senescent cells, and they build up in our bodies as we get older, and we know that they're responsible for a whole range of age-related diseases. And we've also got drugs that can kill those senescent cells while leaving the rest of the cells in the body intact.
One of the biological processes behind aging is the accumulation of aged senescent cells, and they build up in our bodies as we get older, and we know that they're responsible for a whole range of age-related diseases. And we've also got drugs that can kill those senescent cells while leaving the rest of the cells in the body intact.
One of the biological processes behind aging is the accumulation of aged senescent cells, and they build up in our bodies as we get older, and we know that they're responsible for a whole range of age-related diseases. And we've also got drugs that can kill those senescent cells while leaving the rest of the cells in the body intact.
So we've done experiments using these drugs on mice, and we wait till the mice get to about 24 months old. Now mice obviously have a much shorter lifespan than humans, so that's something equivalent to about 70 in human years. So that means we give these old mice the drugs, it clears out those aged cells, and what we find is that the mice basically get biologically younger.
So we've done experiments using these drugs on mice, and we wait till the mice get to about 24 months old. Now mice obviously have a much shorter lifespan than humans, so that's something equivalent to about 70 in human years. So that means we give these old mice the drugs, it clears out those aged cells, and what we find is that the mice basically get biologically younger.
So we've done experiments using these drugs on mice, and we wait till the mice get to about 24 months old. Now mice obviously have a much shorter lifespan than humans, so that's something equivalent to about 70 in human years. So that means we give these old mice the drugs, it clears out those aged cells, and what we find is that the mice basically get biologically younger.