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Anna Greka

👤 Person
316 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And so there's, you know, ASO, siRNA technologies, and then also actual gene editing technologies that we are investigating.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

But I would say that, you know, some of them are closer than others.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And again, to your question about patients, I tell them, honestly, when a project looks to be more promising.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And I also tell them when a project looks to have hurdles and that it will take long and that sometimes I just don't know how long it will take before we can get there.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

So the only thing that I can promise patients,

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

In any of our projects, whether it's Alzheimer's, blindness, kidney disease, all I can promise is that we're working the hardest we possibly can on the problem.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And I think that is often reassuring, I have found, to patients.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And it's best to be honest about the fact that these things take a long time.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

But I do think that they find it reassuring that someone is on it.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

essentially, and that there will be some progress as we move forward.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And we've made progress.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

In the very first discovery that came out of my lab, as I mentioned to you, we've made it all the way to phase two trials.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

So I have seen the trajectory be realized, and I'm eager to make it happen again and again as many times as I can within my career to help as many people as possible.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

I think you're absolutely right.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And this is, again, something that in my leadership of the ACI, I have made sort of a cornerstone of our efforts.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

I think that it has been well documented as a problem.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

I think that the pressures of modern clinical care are really antithetical to the needs of research.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

you know, protected time to really be able to think and be creative and, you know, even have the funding available to be able to, you know, pursue one's program.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

I think those pressures are becoming so heavy for investigators that many of them, you know, kind of choose one or the other route, most often the clinical route, because, you know, that tends to be, of course, where they can support their families better.

Ground Truths
Anna Greka: Molecular Sleuthing for Rare Diseases

And so this has been...