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Aurelia Song

๐Ÿ‘ค Speaker
206 total appearances

Appearances Over Time

Podcast Appearances

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

It took me nine months to create ASC.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

It took me nine years to modify it to work in our current legal context and write those three modifications above.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

I won't get into those nine years in this post.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

I do want to share an image, though, that I'm publishing here for the first time.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

As far as I know this is the best preserved whole human brain in the world, and it belongs to a 46-year-old man who died of ALS and chose to donate his body for scientific research.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

I perfused his body just 90 minutes post-mortem, much faster than typical emergency cryopreservation services, but well outside the 12-minute ischemic window.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

There's an image here.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

It is the best-preserved whole human brain I've ever seen.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

It is also, like every other human brain I preserved with any appreciable post-mortem delay, not traceable.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

It's not a quality I, or the BPF, can accept.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

Looking at the degree of damage scares me.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

I originally thought that humans might have a two-hour post-mortem preservation window.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

If that had been true, I would have probably worked to integrate preservation into hospices across the country.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

After reviewing the electron micrographs from animals and humans under various preservation conditions, it became clear that the hospice model was non-viable.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

We couldn't wait for a person to die on their own timeline and only then begin our procedure.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

We'd need them to undergo a full process involving medical aid in dying, made, and before we could promise any benefits from such a process, we needed to perfect it on animals.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

It took a lot of refinement and expert consultation, but eventually we pinned down the 12-minute window and blood thinner through a series of experiments on rats.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

We then streamlined the procedure so it could be done in less than 10 minutes on pig carcasses and finally demonstrated excellent post-mortem preservation in a pig model.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

We've just recently published the results.

LessWrong (Curated & Popular)
"Nullius in Verba" by Aurelia

There's an image here.