Betül Kaçar

I cannot separate the two.

I think what makes this machinery fascinating is that those five components that I listed, they coexist.

So for instance, if we, let's just...

Talking about the chemistry part, we know the certain rate constant all these proteins that operate in this machinery needs to harbor in order to get the mechanism going.

If you are bringing the information to the translation machinery and you are the initiator of this computation system, you can only afford a certain range of mistakes.

If you're too fast, then the next message cannot be delivered fast.

If you're too slow, then you may stall the process.

So there is definitely a chemistry constant going on within the machinery.

Again, it's not perfect, far from it, but they all have their own margin of error that they can tolerate versus they cannot, otherwise the system collapses.

I like that you said jazz.

It's definitely true.

It's a party and it's like everybody's invited and they need to operate together, right?

And what's really cool about it, I think, there are many things that are very interesting about this thing, but if you remove it from the cell and put it in a cell-free environment, it

works just fine, right?

So you can get cell-free translation systems.

Put this translation in a test tube and it is

doing its thing.

It doesn't need the rest of the cell to translate information.

Of course, you need to feed the information, at least so far, because we are far from evolving a translation, maybe not so far, evolving a translation in the lab or a machinery that can process information as it generates it.

We have not done that yet.