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Beth Shapiro

👤 Person
1835 total appearances

Appearances Over Time

Podcast Appearances

The Joe Rogan Experience
#2338 - Beth Shapiro

And also things like bacteria and microbes get in there and chew up the DNA to recycle the animal to the next generation or plant or whatever.

The Joe Rogan Experience
#2338 - Beth Shapiro

And so the DNA that we get in an old thing, like a mammoth bone, is really short fragments, like maybe 30 or 40 or 50 letters of DNA long.

The Joe Rogan Experience
#2338 - Beth Shapiro

In comparison, if I were to take a swab from my cheek and sequence that, I could get strings that are hundreds of millions of letters long.

The Joe Rogan Experience
#2338 - Beth Shapiro

So ancient DNA is in really crap condition.

The Joe Rogan Experience
#2338 - Beth Shapiro

And it's also mixed with stuff.

The Joe Rogan Experience
#2338 - Beth Shapiro

So if I extract DNA from a mammoth.

The Joe Rogan Experience
#2338 - Beth Shapiro

I'll get some mammoth DNA, but I'll get a lot of those microbes that are in there chewing up DNA.

The Joe Rogan Experience
#2338 - Beth Shapiro

I'll probably get some of my DNA because I touched that mammoth bone.

The Joe Rogan Experience
#2338 - Beth Shapiro

I'll get DNA from whoever else touched that thing.

The Joe Rogan Experience
#2338 - Beth Shapiro

This has been a real problem in archaeology because we're trying to get DNA from humans, but we are humans.

The Joe Rogan Experience
#2338 - Beth Shapiro

And so we touch these things and then I don't know if it's my DNA or if that thing DNA.

The Joe Rogan Experience
#2338 - Beth Shapiro

Yeah, or dropping an eyelash.

The Joe Rogan Experience
#2338 - Beth Shapiro

Went in my lab at Santa Cruz and in ancient DNA labs around the world.

The Joe Rogan Experience
#2338 - Beth Shapiro

We have these really, it's like working in a virus lab where you're scared of everything, but we turn it around.

The Joe Rogan Experience
#2338 - Beth Shapiro

So rather than having the air being sucked in, we're kind of trying to push the air out.

The Joe Rogan Experience
#2338 - Beth Shapiro

We don't want any air coming in.

The Joe Rogan Experience
#2338 - Beth Shapiro

We wear these suits where it looks like we're terrified, you know, with a face mask and hair net and we're totally covered and we bleach everything.

The Joe Rogan Experience
#2338 - Beth Shapiro

It's not because we're afraid of those bones.

The Joe Rogan Experience
#2338 - Beth Shapiro

We're afraid that we're going to get our DNA in that bone and then we're not going to be able to do our work.