Bethany Brookshire
👤 PersonAppearances Over Time
Podcast Appearances
Like right all the way down to DNA.
Like right all the way down to DNA.
Like right all the way down to DNA.
If you want an animal to press a lever and receive a drug, a rat is generally the better choice.
If you want an animal to press a lever and receive a drug, a rat is generally the better choice.
If you want an animal to press a lever and receive a drug, a rat is generally the better choice.
Especially now with the advent of CRISPR technologies that allow us to alter adult genetics and fetal genetics, we established that first in mice. We can do it in rats now, but it's very, very well established in mice. And so that really took off.
Especially now with the advent of CRISPR technologies that allow us to alter adult genetics and fetal genetics, we established that first in mice. We can do it in rats now, but it's very, very well established in mice. And so that really took off.
Especially now with the advent of CRISPR technologies that allow us to alter adult genetics and fetal genetics, we established that first in mice. We can do it in rats now, but it's very, very well established in mice. And so that really took off.
Yes. In my experience, rats are better for self-administration of drugs. So if you want an animal to press a lever and receive a drug, a rat is generally the better choice because of size. Because mice are so small, it's really hard to make a lever that they can press well enough.
Yes. In my experience, rats are better for self-administration of drugs. So if you want an animal to press a lever and receive a drug, a rat is generally the better choice because of size. Because mice are so small, it's really hard to make a lever that they can press well enough.
Yes. In my experience, rats are better for self-administration of drugs. So if you want an animal to press a lever and receive a drug, a rat is generally the better choice because of size. Because mice are so small, it's really hard to make a lever that they can press well enough.
I studied primarily drugs of abuse in graduate school, and then I studied antidepressants for my postdoc.
I studied primarily drugs of abuse in graduate school, and then I studied antidepressants for my postdoc.
I studied primarily drugs of abuse in graduate school, and then I studied antidepressants for my postdoc.
Ritalin, cocaine, methamphetamine, ecstasy, alcohol, Prozac. If you want to be really nerdy about it, I studied the dopamine-serotonergic interactions in the ventral tegmental area nucleus accumbens circuit of the mouse brain.
Ritalin, cocaine, methamphetamine, ecstasy, alcohol, Prozac. If you want to be really nerdy about it, I studied the dopamine-serotonergic interactions in the ventral tegmental area nucleus accumbens circuit of the mouse brain.
Ritalin, cocaine, methamphetamine, ecstasy, alcohol, Prozac. If you want to be really nerdy about it, I studied the dopamine-serotonergic interactions in the ventral tegmental area nucleus accumbens circuit of the mouse brain.
Yeah. So I was interested in drugs that primarily targeted dopaminergic systems.
Yeah. So I was interested in drugs that primarily targeted dopaminergic systems.