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Betül Kaçar

👤 Person
1202 total appearances

Appearances Over Time

Podcast Appearances

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

But in terms of chemistry, you absolutely cannot have a translation machinery without chemistry.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And so, as I said, there are four main steps.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

These are the core steps that are conserved in all translation machinery.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

And I should say, all life has this machine, right?

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Every cell, everything.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

On Earth.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yeah.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yes.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Yes.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

I cannot separate the two.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

I think what makes this machinery fascinating is that those five components that I listed, they coexist.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So for instance, if we, let's just...

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Talking about the chemistry part, we know the certain rate constant all these proteins that operate in this machinery needs to harbor in order to get the mechanism going.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

If you are bringing the information to the translation machinery and you are the initiator of this computation system, you can only afford a certain range of mistakes.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

If you're too fast, then the next message cannot be delivered fast.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

If you're too slow, then you may stall the process.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

So there is definitely a chemistry constant going on within the machinery.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

Again, it's not perfect, far from it, but they all have their own margin of error that they can tolerate versus they cannot, otherwise the system collapses.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

I like that you said jazz.

Lex Fridman Podcast
#350 – Betül Kaçar: Origin of Life, Ancient DNA, Panspermia, and Aliens

It's definitely true.