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StarTalk Radio

How Did Life Begin? with Betül Kaçar

05 May 2026

Transcription

Chapter 1: What foundational questions do we ask about life in the universe?

0.065 - 21.718 Neil deGrasse Tyson

You know, all our efforts to find life in the universe at some point needs a ground truth. So true. And that happens on Earth. Yes. We got one of the world's experts to think about life on Earth and how it got here and how it turned into what it became. Yeah. Going back three billion years. Or we're going into the way back. Way. Way back. Coming up on StarTalk.

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22.306 - 39.768 Neil deGrasse Tyson

What would you do if an alien actually showed up? Would you shake its hand or run? Does it even have a hand to shake? In my latest book, Take Me to Your Leader, I explore not only how they might have gotten here, but what they might want and how you should respond.

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Chapter 2: How do experts define life on Earth and elsewhere?

40.148 - 69.549 Neil deGrasse Tyson

Because the real question is not, are we alone? It's, are we ready? By the way, I also narrated Take Me to Your Leader. And I'm duly informed that you can get a copy of that book or the audio book now, wherever books are sold. You should probably get the book sooner rather than later. You don't want to have a first alien encounter and not be ready for it. I'm just saying. Welcome to StarTalk.

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70.39 - 92.149 Neil deGrasse Tyson

Your place in the universe where science and pop culture collide. StarTalk begins right now. This is StarTalk. Neil deGrasse Tyson, your personal astrophysicist, got Chuck Nice with me. What's up, Neil? Chuck, it's about time we cover this subject. Okay.

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Chapter 3: What insights does Betül Kaçar provide about ancient enzymes?

92.169 - 100.767 Chuck Nice

It's life on Earth and in the heavens. It is about time because, you know, it's been about four billion years. Like when the hell are we going to get to?

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100.827 - 122.056 Neil deGrasse Tyson

Might as well do it now. Might as well do it now. And there's an interesting diversity of expertise out there. Everybody taking the little bit of what their background enables them to study and contribute to our understanding of what life is and what makes it tick and what's the difference between life here and elsewhere. What do you mean elsewhere?

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122.577 - 127.926 Neil deGrasse Tyson

We're going to find out. Oh, okay. We have with us, Beetool Kachar.

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128.307 - 128.427 Betül Kaçar

Hi.

128.748 - 129.329 Neil deGrasse Tyson

Hello.

129.509 - 130.491 Betül Kaçar

Hi, thanks for having me.

Chapter 4: How do microbial processes shape the planet's history?

130.972 - 132.434 Neil deGrasse Tyson

Welcome to StarTalk.

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132.454 - 133.095 Betül Kaçar

Happy to be here.

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133.215 - 154.167 Neil deGrasse Tyson

All right, so you got all the pedigree here that's necessary for this conversation. Director of the NASA-funded MIT. Muse. Metal utilization and selection across eons. Oh, wow. We got to get into, what's that about? Yeah, and there's the eons. And there's a Kachar lab. Did you found your own lab? Is that right?

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154.407 - 156.41 Betül Kaçar

Yeah, yeah. I run my own lab.

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156.51 - 157.251 Neil deGrasse Tyson

Nice.

Chapter 5: What role do extremophiles play in our understanding of life?

157.371 - 160.536 Neil deGrasse Tyson

People have their own labs? That's badass. That's badass. It's pretty cool.

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160.616 - 163.62 Chuck Nice

That's, that's, that's. It's very Marie Curie of you.

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164.545 - 165.766 Betül Kaçar

I hope my ending is the same.

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166.026 - 166.327 Neil deGrasse Tyson

No!

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166.567 - 167.388 Betül Kaçar

Well, the good part.

167.588 - 172.333 Neil deGrasse Tyson

Okay. That means if you create something in your lab, it comes after you first. Yeah.

172.493 - 176.256 Unknown

Yes, I live with that fact every day.

176.356 - 179.76 Neil deGrasse Tyson

You are Professor at University of Wisconsin, Madison. Nice.

Chapter 6: How does nitrogen fixation impact our planet's ecosystems?

179.78 - 189.669 Neil deGrasse Tyson

In the Department of Bacteriology. Wow. Ooh. So if you have that on a business card and you hand that to someone, do they just walk away from you? Or do they use gloves to take your card?

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189.769 - 191.491 Betül Kaçar

Well, let me tell you, I don't have a lot of friends because of this.

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191.651 - 193.573 Neil deGrasse Tyson

That's what I'm wondering.

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193.553 - 199.663 Betül Kaçar

Yeah. But if you don't like bacteria, we can't be friends. So let's get that straight. Are we bacteria friendly here?

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200.063 - 204.33 Chuck Nice

Yeah, we are. Okay, good. Very good. Very good.

Chapter 7: What implications does astrobiology have for understanding life's origins?

204.35 - 210.82 Chuck Nice

Without it, would we even be? Would we even be? We wouldn't be. We would not be without bacteria, right? We wouldn't be able to breathe. Yeah, we wouldn't be.

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210.8 - 213.623 Betül Kaçar

You would make an attempt, but there wouldn't be any oxygen to breathe.

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213.644 - 214.565 Neil deGrasse Tyson

Or digest our food.

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214.965 - 216.227 Betül Kaçar

Right. So many things.

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216.307 - 223.896 Neil deGrasse Tyson

It does the digesting. It does all the digesting, right? Right, right. Okay. See, we're friendly.

Chapter 8: How can studying life's past inform our future?

223.916 - 224.517 Betül Kaçar

I wanted to make sure.

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225.779 - 249.526 Neil deGrasse Tyson

So you recently published a paper in Nature, which is the preeminent European journal of science. And it's you... you resurrected ancient enzymes? What does that even mean? It's kind of scary though. To resurrect anything as a biologist, that's got Jurassic Park written all over it.

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249.626 - 256.112 Chuck Nice

Oh, I was going with Jesus, but okay, I'll take the Jurassic Park.

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256.213 - 262.339 Neil deGrasse Tyson

They both start with a J. Exactly. So tell me what was the significance of that paper?

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262.42 - 286.151 Betül Kaçar

Well, as you said in the beginning, there are many ways in which a scientist can study life. And we are, I would say, obsessed with understanding its origins and its first steps. Mind you, it's a bit different than life's origin. We are interested in what happened once life emerged. And what were the first steps and how did life survive over eons, over billions of years?

286.271 - 308.48 Betül Kaçar

And how did it make it through this far? We are also interested in understanding the marks that life leaves behind. So if I walk in the snow, you can tell my footsteps at least for some time and then snow melts and my marks are gone, right? If I leave that kind of mark on rocks, like if I'm a dinosaur, you're able to track my past as well using this. But if I'm a microbe, How does this work?

308.54 - 315.236 Betül Kaçar

And we know that this is a microbial planet. Our planet is run by microbes. If you don't like microbes, wrong place for you.

315.256 - 318.143 Chuck Nice

So Beyonce was wrong. Who run the world? Not girls, microbes.

318.324 - 321.992 Betül Kaçar

And girls. See what happens?

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