Bliss Chapman

So what you're seeing is in this kind of macro image, you're seeing these like circle highlighted in white, the insertion sites. And when you zoom into one of those, you see the threads. And then in this particular case, I think we're seeing about the 16 wires that are going into the page.

So what you're seeing is in this kind of macro image, you're seeing these like circle highlighted in white, the insertion sites. And when you zoom into one of those, you see the threads. And then in this particular case, I think we're seeing about the 16 wires that are going into the page.

And the incredible thing here is the fact that you have the neurons that are these brown structures or brown circular or elliptical thing that are actually touching and abutting the threads. So what this is saying is that there's basically zero trauma that's caused during this insertion.

And the incredible thing here is the fact that you have the neurons that are these brown structures or brown circular or elliptical thing that are actually touching and abutting the threads. So what this is saying is that there's basically zero trauma that's caused during this insertion.

And the incredible thing here is the fact that you have the neurons that are these brown structures or brown circular or elliptical thing that are actually touching and abutting the threads. So what this is saying is that there's basically zero trauma that's caused during this insertion.

And with these neural interfaces, these micro electrodes that you insert, that is one of the most common mode of failure. So when you... insert these threads like the Utah ray, it causes neuronal death around the site because you're inserting a foreign object, right? And that kind of elicit these like immune response through microglia and astrocytes. They form this like protective layer around it.

And with these neural interfaces, these micro electrodes that you insert, that is one of the most common mode of failure. So when you... insert these threads like the Utah ray, it causes neuronal death around the site because you're inserting a foreign object, right? And that kind of elicit these like immune response through microglia and astrocytes. They form this like protective layer around it.

And with these neural interfaces, these micro electrodes that you insert, that is one of the most common mode of failure. So when you... insert these threads like the Utah ray, it causes neuronal death around the site because you're inserting a foreign object, right? And that kind of elicit these like immune response through microglia and astrocytes. They form this like protective layer around it.

Not only are you killing the neuron cells, but you're also creating this protective layer that then basically prevents you from recording neural signals because you're getting further and further away from the neurons that you're trying to record. And that is the biggest mode of failure. And in this particular example, in that inset, it's about 50 micron with that scale bar.

Not only are you killing the neuron cells, but you're also creating this protective layer that then basically prevents you from recording neural signals because you're getting further and further away from the neurons that you're trying to record. And that is the biggest mode of failure. And in this particular example, in that inset, it's about 50 micron with that scale bar.

Not only are you killing the neuron cells, but you're also creating this protective layer that then basically prevents you from recording neural signals because you're getting further and further away from the neurons that you're trying to record. And that is the biggest mode of failure. And in this particular example, in that inset, it's about 50 micron with that scale bar.

The neurons just seem to be attracted to it. Yeah.

The neurons just seem to be attracted to it. Yeah.

The neurons just seem to be attracted to it. Yeah.

And the way that these things, I mean, your tissues generally don't have these beautiful colors. This is a multiplex stain that uses these different proteins that are staining these at different colors. We use a very standard set of staining techniques with HE, EVA1, and NUEN, and GFAP. So if you go to the next image, this is also kind of illustrates the second point.

And the way that these things, I mean, your tissues generally don't have these beautiful colors. This is a multiplex stain that uses these different proteins that are staining these at different colors. We use a very standard set of staining techniques with HE, EVA1, and NUEN, and GFAP. So if you go to the next image, this is also kind of illustrates the second point.

And the way that these things, I mean, your tissues generally don't have these beautiful colors. This is a multiplex stain that uses these different proteins that are staining these at different colors. We use a very standard set of staining techniques with HE, EVA1, and NUEN, and GFAP. So if you go to the next image, this is also kind of illustrates the second point.

Cause you can make an argument. And initially when we saw the previous image, we said, oh, like, are the threads just floating? Like what is happening here? Like, are we actually looking at the right thing? So what we did is we did another stain and this is all done in-house.

Cause you can make an argument. And initially when we saw the previous image, we said, oh, like, are the threads just floating? Like what is happening here? Like, are we actually looking at the right thing? So what we did is we did another stain and this is all done in-house.

Cause you can make an argument. And initially when we saw the previous image, we said, oh, like, are the threads just floating? Like what is happening here? Like, are we actually looking at the right thing? So what we did is we did another stain and this is all done in-house.