Bliss Chapman
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of this masson's uh trichrome stain which is in blue that shows these collagen layers so the blue basically like you don't want the blue around the implant threads because that means that there's some sort of scarring that's happened and what you're seeing if you look at individual threads is that you don't see any of the blue which means that there has been absolutely or very very minimal to a point where it's not detectable amount of trauma in these inserted threads
of this masson's uh trichrome stain which is in blue that shows these collagen layers so the blue basically like you don't want the blue around the implant threads because that means that there's some sort of scarring that's happened and what you're seeing if you look at individual threads is that you don't see any of the blue which means that there has been absolutely or very very minimal to a point where it's not detectable amount of trauma in these inserted threads
of this masson's uh trichrome stain which is in blue that shows these collagen layers so the blue basically like you don't want the blue around the implant threads because that means that there's some sort of scarring that's happened and what you're seeing if you look at individual threads is that you don't see any of the blue which means that there has been absolutely or very very minimal to a point where it's not detectable amount of trauma in these inserted threads
Yeah, so we think this is primarily due to the size as well as the flexibility of the threads. Also the fact that R1 is avoiding vasculature, so we're not disrupting or we're not causing damage to the vessels and not breaking any of the blood-brain barrier has basically caused the immune response to be muted.
Yeah, so we think this is primarily due to the size as well as the flexibility of the threads. Also the fact that R1 is avoiding vasculature, so we're not disrupting or we're not causing damage to the vessels and not breaking any of the blood-brain barrier has basically caused the immune response to be muted.
Yeah, so we think this is primarily due to the size as well as the flexibility of the threads. Also the fact that R1 is avoiding vasculature, so we're not disrupting or we're not causing damage to the vessels and not breaking any of the blood-brain barrier has basically caused the immune response to be muted.
Yeah. Those are neurons.
Yeah. Those are neurons.
Yeah. Those are neurons.
Yeah, so what you're looking at is not electrodes themselves. Those are the conductive wires. So each of those should probably be two micron in width. So what we're looking at is we're looking at the coronal slice. So we're looking at some slice of the tissue. So as you go deeper, you'll obviously have less and less of the tapering. of the thread.
Yeah, so what you're looking at is not electrodes themselves. Those are the conductive wires. So each of those should probably be two micron in width. So what we're looking at is we're looking at the coronal slice. So we're looking at some slice of the tissue. So as you go deeper, you'll obviously have less and less of the tapering. of the thread.
Yeah, so what you're looking at is not electrodes themselves. Those are the conductive wires. So each of those should probably be two micron in width. So what we're looking at is we're looking at the coronal slice. So we're looking at some slice of the tissue. So as you go deeper, you'll obviously have less and less of the tapering. of the thread.
But yeah, the point basically being that there's just kind of cells around the insert site, which is just an incredible thing to see. I've just never seen anything like this. How easy and safe is it to remove the implant? Yeah, so it depends on when. In the first three months or so after the surgery, there's a lot of kind of tissue modeling that's happening.
But yeah, the point basically being that there's just kind of cells around the insert site, which is just an incredible thing to see. I've just never seen anything like this. How easy and safe is it to remove the implant? Yeah, so it depends on when. In the first three months or so after the surgery, there's a lot of kind of tissue modeling that's happening.
But yeah, the point basically being that there's just kind of cells around the insert site, which is just an incredible thing to see. I've just never seen anything like this. How easy and safe is it to remove the implant? Yeah, so it depends on when. In the first three months or so after the surgery, there's a lot of kind of tissue modeling that's happening.
You know, similar to when you get a cut, you know, you obviously, you know, start over first couple weeks or depending on the size of the wound, scar tissue forming, right? There are these like contracted and then in the end, they turn into scab and you can scab it off. The same thing happens in the brain. And it's a very dynamic environment.
You know, similar to when you get a cut, you know, you obviously, you know, start over first couple weeks or depending on the size of the wound, scar tissue forming, right? There are these like contracted and then in the end, they turn into scab and you can scab it off. The same thing happens in the brain. And it's a very dynamic environment.
You know, similar to when you get a cut, you know, you obviously, you know, start over first couple weeks or depending on the size of the wound, scar tissue forming, right? There are these like contracted and then in the end, they turn into scab and you can scab it off. The same thing happens in the brain. And it's a very dynamic environment.
And before the scar tissue or the neomembrane or the new membrane that forms, it's quite easy to just pull them out. And there's minimal trauma that's caused during that. Once the scar tissue forms, and with Nolan as well, we believe that that's the thing that's currently anchoring the threads. So we haven't seen any more movements since then. So they're quite stable.
And before the scar tissue or the neomembrane or the new membrane that forms, it's quite easy to just pull them out. And there's minimal trauma that's caused during that. Once the scar tissue forms, and with Nolan as well, we believe that that's the thing that's currently anchoring the threads. So we haven't seen any more movements since then. So they're quite stable.