Brian Armstrong

My conversations are sometimes a lot more mundane about like, how do I get these two people to work together, you know?

But we still got to solve all the human problems before we start building interplanetary financial systems.

Yeah, well, actually, Jacob Kimmel and Blake and I all started it together as co-founders, and Jacob's the CEO now, so he's really running it day to day.

He's brilliant.

Yeah, he is.

Yeah, so the origin story goes actually back to the IPO of Coinbase, believe it or not, and 2021, having gotten some liquidity from Coinbase and thinking about the next 10 years and what were going to be the big technology trends that could drive civilizational progress, I kind of felt like a lot of the big ones had good teams working on it, right?

AI and

fusion energy and brain machine interfaces and all the rest space.

One that I didn't see great teams working on as much and that maybe seemed underfunded was longevity.

And so I reached out to a few folks, started hosting some dinners with just top scientists and biotech CEOs and kind of went around the table and said, all right, what's on the horizon that's most exciting to you, but it's underfunded?

And one of the folks mentioned epigenetic reprogramming, which is this area that talks about how you can reprogram cells.

Shinya Yamanaka famously won the Nobel Prize for this in 2012, showing you could reprogram an old skin cell into a young embryonic stem cell.

And he, by doing so with just these four proteins added to the cell, he had this kind of remarkable discovery that he changed both the age of the cell and the type of the cell.

So at New Limit, we're trying to do half of what Shinya Yamanaka did.

We don't want to change the type of the cell.

We just want to change the age.

And what we mean by that is really just restoring the function that the cell had when it was younger.

And...

We built a high throughput screening system.

It starts with AI to explore the, you know, 10 quadrillion different possibilities, combinations of different proteins you could use to reprogram a cell.