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Brian Armstrong

πŸ‘€ Speaker
1465 total appearances

Appearances Over Time

Podcast Appearances

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

And it starts to, it originally ingested all of the existing literature.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

Now it's been ingesting the wet lab data that's been coming out of New Limit, which we have the largest data set out there by far.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

And so it recommends the next set of experiments that we run in our wet lab.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

We do these pooled screens and see if,

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

phenotypically, we can make cells look younger.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

Then we take the best hits out of that in the funnel and we put them through functional assays, which are a little slower and more expensive, to see if they actually act younger.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

For instance, we might take a reprogrammed liver cell and see if it can process caffeine and acetaminophen and alcohol or whatever, kind of like a young liver cell.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

And then the best functional assay candidates we then are starting to run through are

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

non-human primate and human trials.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

So yeah, the process has gone faster than I would have expected.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

I thought this was going to be like a five or 10 year kind of basic research endeavor, but we've actually been able to demonstrate successful reprogramming of human cells now in our first drug candidates going into the clinic next year, hopefully followed by a bunch more.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

I have to go look at his data on that.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

I actually, I haven't looked at the exact year that it would be projected to happen.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

I'm just been, again, trying to solve more mundane problems.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

Like how do we hire, how do we hire the next, you know, bioinformaticist or whatever.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

But yeah, I hope he's right.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

I mean, he has been right on so many things.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

It wouldn't surprise me if he's right again.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

Actually, I like your theory.

Moonshots with Peter Diamandis
Brian Armstrong on Bitcoin, Anthropic Drops Fable 5 & Mythos 5, NewLimit's $435M Age-Reversal | EP #264

I like your theory on that, Alex.