Brigham Buhler
speaker
1,533 appearances
6 recordings
5 series
first heard Oct 2024
last heard 27 Feb
Brigham Buhler’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Feb 2026 with 1.
Appearances
And the whole time it's sitting in a trunk that's literally 150 fucking degrees. There's so many. People are just unaware that it's not what it is portrayed to be. The environment is not as safe as it's portrayed to be. Trust but verify. Do your research. Do your homework. Don't take surgery lightly. Know that everything is a calculated risk.
And that's why I'm such an advocate for like preventative proactive care, getting predictive, prevent chronic disease. If you want to stop the five chronic diseases that are killing people and running up health care and causing bankruptcy, let's start with not letting them fucking develop in the first place. What are those five?
You got atherosclerosis, heart disease, all of it stems from metabolic disease, cancer rates, all of every single one of the big five killers of mankind go back to metabolic health.
And so when we were talking about how do we fix the healthcare system, even a neurocognitive decline, second to age, your biggest in smoking, your biggest risk, if you don't, if other than age and smoking, the third biggest risk factor on any of the big five is metabolic disease and metabolic health. So one of the things Callie says is it's very easy to fix our healthcare system overnight.
We incentivize metabolic health. We drive metabolic health. If we really want to fix the root cause of all of these chronic diseases that are cascading and self-fulfilling prophecies, let's just fix metabolic health. And make that the focus of primary cares and make that the focus of our health care institutions and incentivize humanity or Americans to have great metabolic health.
I don't remember where it's terrible. I think we're like 60th or something on like I don't remember that. I don't want to misquote that one, but it's not good. Like the age of men in Japan, their life expectancy is higher. Women all over the world, their life expectancy is higher. Our cancer rates are at all time high. All the things are deaths of despair at an all time high.
It's the worst of almost all developed countries. But we spend more than almost every other nation on our health care. I mean, it's just mind boggling. But.
it's it's but it's not as dire it's not as impossible to fix as people are making it out to be it really all comes down to incentives like i said earlier like show me the incentives i'll show you the outcomes if we incentivize the average american and the average clinician in america to get proactive and predictive if we had a paradigm shift where people realize that their health insurance
is more like car insurance. It's there if you total the car. It's there if something catastrophic happens. But you should not be putting your... They're not going to rotate the tires, change the oil, and maintain the vehicle. It's your job to... to take sovereignty and accountability over your health. It's your job to identify these things.
And I think the way of the future is large language models, algorithm-based medicine, you know, like the app we're launching at Wastewell monitors you 24-7, ties into your wearables. We've got a chat bot, Alan, that's an AI bot that literally answers any question, pulls from your medical records, and gets it right better than most clinicians.
annotates all of your calls, loads all your questions in for whenever you get on a call with a doctor, and it's all documented. But that's not unique to us. I think the world is headed that way. And with algorithm-based medicine, I don't think in five years people will even go to a primary care. I really don't.
I think you're going to have an app in your pocket that monitors your blood sugar, your glucose, all of your blood levels daily. And it's not just a snapshot of you in time every six months or whenever you get time to go get your blood work done fasted. It's literally swallow this pill in the morning, five minutes before you eat.
That pill tells the iPhone or the app everything that's going on in your body. And we can begin to project all-cause mortality risk. And through that, we can drive down chronic disease risk.
And so if we know, like, let's say we have your epigenetics and we know that epigenetics are the gun and then your lifestyle choices and decisions are the bullets that you load the gun with and pull the trigger.
Now we can track not only your epigenetics, but also your active biomarkers, but also your behaviors, your exercise, how many hours of sleep you're getting, your deep sleep, your REM sleep, your heart rate variability. And we can begin to project out all cause mortality risk. And the beauty of that is we can now begin to drive down those risk factors. That's the future of medicine.
That's where this is headed.
I think in the next 24 months, like I think in the next 24 months, a lot of this will be executed in the next 24 months and it won't just be waged. Well, I think there'll be dozens, if not hundreds of companies and there's a billionaire's arms race into this sector. Now there's so many billionaires getting into the space and putting money into the space and trying to figure it out.
And there's that component. Then there's the large language models and AI's ability to, you know, uh, hack the genome down to different levels. And so like one of my friends and mentors, Dr. Ian White, he's brilliant, like you would love him, but he's actually a Brit too. Very good, I like him already. He's from Harvard and 22 years at the bench. His theory is we share a common ancestor
with the eternal jellyfish, which lives over 5,000 years. We share a common ancestor with the Galapagos tortoise, which lives over 200 years. We share a common ancestor with the Greenland shark, which has no cancer and lives over 600 years. All of those black boxes are within our genetics.
With AI and large language models and quantum computing, how quickly is a scientist going to crack that code? Somebody's going to do it. And so my pitch is like, you've got, you know, the Gary Brekkas and the people saying, we think you're going to live to be 150. I'm not that optimistic of that. I think we can drive hell span like what Peter says.
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