Calley Means
π€ SpeakerAppearances Over Time
Podcast Appearances
But what I get excited about is that that person in that aisle who has made the commitment to try to lose weight, to try to be healthier, is not at the mercy of the food marketing, of what the box says. They actually have some agency now in the face of unfortunately, industries that are not necessarily aligned with our long-term health. So those are some of the surprising ones that we've seen.
But what I get excited about is that that person in that aisle who has made the commitment to try to lose weight, to try to be healthier, is not at the mercy of the food marketing, of what the box says. They actually have some agency now in the face of unfortunately, industries that are not necessarily aligned with our long-term health. So those are some of the surprising ones that we've seen.
Well, this is such an important question because I want to be very clear. Glucose is not the only biomarker that you need to orient your diet around. Right now, it's the only continuous biomarker that we have that can give us closed-loop biofeedback on nutrition. we don't have anything else that we can put on our bodies and see exactly how food's affecting us.
Well, this is such an important question because I want to be very clear. Glucose is not the only biomarker that you need to orient your diet around. Right now, it's the only continuous biomarker that we have that can give us closed-loop biofeedback on nutrition. we don't have anything else that we can put on our bodies and see exactly how food's affecting us.
Well, this is such an important question because I want to be very clear. Glucose is not the only biomarker that you need to orient your diet around. Right now, it's the only continuous biomarker that we have that can give us closed-loop biofeedback on nutrition. we don't have anything else that we can put on our bodies and see exactly how food's affecting us.
You know, I think, of course, both you and I would probably love to see an inflammatory monitor, an oxidative stress monitor, you know, these things that also affect our health.
You know, I think, of course, both you and I would probably love to see an inflammatory monitor, an oxidative stress monitor, you know, these things that also affect our health.
You know, I think, of course, both you and I would probably love to see an inflammatory monitor, an oxidative stress monitor, you know, these things that also affect our health.
Insulin. Insulin, of course.
Insulin. Insulin, of course.
Insulin. Insulin, of course.
Of course. And so that's what kind of gets into the things that won't spike glucose, but you still should avoid for optimal metabolic health. The first and the biggest one is fructose. So fructose alone... will not spike blood sugar or insulin. But we know from the mechanisms of how insulin resistance develops that it directly contributes to insulin resistance through a really interesting pathway.
Of course. And so that's what kind of gets into the things that won't spike glucose, but you still should avoid for optimal metabolic health. The first and the biggest one is fructose. So fructose alone... will not spike blood sugar or insulin. But we know from the mechanisms of how insulin resistance develops that it directly contributes to insulin resistance through a really interesting pathway.
Of course. And so that's what kind of gets into the things that won't spike glucose, but you still should avoid for optimal metabolic health. The first and the biggest one is fructose. So fructose alone... will not spike blood sugar or insulin. But we know from the mechanisms of how insulin resistance develops that it directly contributes to insulin resistance through a really interesting pathway.
Fructose is broken down into a byproduct called uric acid, which goes into the mitochondria, the seed of our metabolism in the cell, and generates oxidative stress, this damaging free radical activity that actually causes the mitochondria to become dysfunctional and process glucose less effectively and shunt glucose to fat storage.
Fructose is broken down into a byproduct called uric acid, which goes into the mitochondria, the seed of our metabolism in the cell, and generates oxidative stress, this damaging free radical activity that actually causes the mitochondria to become dysfunctional and process glucose less effectively and shunt glucose to fat storage.
Fructose is broken down into a byproduct called uric acid, which goes into the mitochondria, the seed of our metabolism in the cell, and generates oxidative stress, this damaging free radical activity that actually causes the mitochondria to become dysfunctional and process glucose less effectively and shunt glucose to fat storage.
So then you start getting fatty liver disease because of fructose, and that fatty liver disease causes liver insulin resistance, which then makes you less...
So then you start getting fatty liver disease because of fructose, and that fatty liver disease causes liver insulin resistance, which then makes you less...
So then you start getting fatty liver disease because of fructose, and that fatty liver disease causes liver insulin resistance, which then makes you less...