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Charlotte Bunne

👤 Person
104 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

They are not going to scale.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And at the same time, I need to be completely flexible in whatever input combination of channel I'm just going to face in this experiment.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So, I mean, so this is what...

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

we right now did, for example, in our very first work, inheriting the design principle that we laid out in the paper, AI virtual cell, and then come up with new AI architectures that are dealing with these very special requirements that biological data have.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

We have now a lot of computer scientists that work very, very closely, have a very good understanding of biologists, biologists that are getting much and much more into the computer science.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So people who are fluent in both languages somewhat that are able to now build models that are adapted and designed for biological data.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And we don't just take basically computer vision architectures that work well on street scenes and try to apply them on biological data.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So it's just a...

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Very different way of thinking about it, starting, constructing basically specialized architectures.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Besides, of course, the tremendous data efforts that have happened in the past.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So I work in particular on the prospect of using this to build diagnostic tools and to make diagnostics in the clinic easier.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Because ultimately, we have somewhat limited capabilities in the hospital to run like deep omics.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

But the idea of being able to somewhat map with cheaper and lighter tools

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

modality or like somehow diagnostic test into something much richer because the model has been seeing all those different data and can basically contextualize it.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

It's very interesting, right?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

We've seen all those pathology foundation models.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

If I can always run an H&E, but then decide when to run deeper diagnostics to have a better or more accurate

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

prediction that is very powerful and is ultimately reducing the costs, but the precision that we have in hospitals.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So my faculty position right now is co-located between the School of Life Sciences, School of Computer Science.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So I have a dual affiliation.