Chris Masterjohn
๐ค SpeakerAppearances Over Time
Podcast Appearances
They picked this year out of history and there's always these big, massive big things all happening in different areas.
But anyway, so there was something in there in 1984.
Maybe it was self-fulfilling prophecy from Orwell.
So the chair of the NIH consensus conference in 1984 was Daniel Steinberg.
Daniel Steinberg passed away a few years ago.
But he was kind of, there were three big names that came out of that conference.
And Steinberg was one of them.
And the others were Brown and Goldstein, who won the Nobel Prize in 1985, the next year, for, you know, you can see how they hooked up their Nobel Prize.
So they, 1985, they got the Nobel Prize for discovering the LDL receptor, which is the thing that brings cholesterol from your blood into your cells.
And all the drugs that work on this
are targeting that receptor.
So that became the springboard for all the drugs that people are on for cardiovascular disease now.
So this is kind of funny that the Nobel Prize was probably in the fix in 1984.
That was the other thing they were working on.
Because there's no way that would have happened if the 1984 consensus conference didn't happen.
But the point I want to make is that Daniel Steinberg
I didn't come up with this idea myself.
I mean, he's dead now, but for decades, he was one of the people who believed that because it was his lab that discovered that the PUFAs, which are seed oil fats, have to become damaged on the outer membrane of the LDL particle for it to get taken up by the immune system.