Chuck

You know if you want to podcast better, put on a neck brace. Apparently, if none of those things work, though, and you are a visiting military soldier and you are attacked, to protect yourself, curl into a ball and protect all of your major internal organs and major arteries.

You know if you want to podcast better, put on a neck brace. Apparently, if none of those things work, though, and you are a visiting military soldier and you are attacked, to protect yourself, curl into a ball and protect all of your major internal organs and major arteries.

You know if you want to podcast better, put on a neck brace. Apparently, if none of those things work, though, and you are a visiting military soldier and you are attacked, to protect yourself, curl into a ball and protect all of your major internal organs and major arteries.

Yeah. No, I mean, that was kind of sad. If you look up drop bear, there's some funny pictures of like just photoshopped koalas that look super scary and mean.

Yeah. No, I mean, that was kind of sad. If you look up drop bear, there's some funny pictures of like just photoshopped koalas that look super scary and mean.

Yeah. No, I mean, that was kind of sad. If you look up drop bear, there's some funny pictures of like just photoshopped koalas that look super scary and mean.

In my mind, I said funny. I guess only the listener will know the truth of which one of us just had a stroke.

In my mind, I said funny. I guess only the listener will know the truth of which one of us just had a stroke.

In my mind, I said funny. I guess only the listener will know the truth of which one of us just had a stroke.

Hey, and welcome to the podcast. I'm Josh, and there's Chuck, and Jerry's here, too. And this is Stuff You Should Know, the Big Bummer Edition.

Hey, and welcome to the podcast. I'm Josh, and there's Chuck, and Jerry's here, too. And this is Stuff You Should Know, the Big Bummer Edition.

Hey, and welcome to the podcast. I'm Josh, and there's Chuck, and Jerry's here, too. And this is Stuff You Should Know, the Big Bummer Edition.

Yes, but there is a slight silver lining. It is possible that it is so deadly and so dangerous that it's actually created a decline in its use. At the very least, a decline in deaths from it has taken place. So it is on the decline, at least deaths. Yeah. And we'll talk about possibly why that is later on. But yeah, we'll talk about the origin of fentanyl.

Yes, but there is a slight silver lining. It is possible that it is so deadly and so dangerous that it's actually created a decline in its use. At the very least, a decline in deaths from it has taken place. So it is on the decline, at least deaths. Yeah. And we'll talk about possibly why that is later on. But yeah, we'll talk about the origin of fentanyl.

Yes, but there is a slight silver lining. It is possible that it is so deadly and so dangerous that it's actually created a decline in its use. At the very least, a decline in deaths from it has taken place. So it is on the decline, at least deaths. Yeah. And we'll talk about possibly why that is later on. But yeah, we'll talk about the origin of fentanyl.

For those of you who don't know, it's a synthetic opioid. First, there was morphine, which is, I think, basically 100% processed natural opium. Heroin is a kind of a combo hybrid between synthetic and natural. And then fentanyl is just straight up like just made up. It's an analog. And it's way more potent than anything anyone had ever seen before when it came on the scene.

For those of you who don't know, it's a synthetic opioid. First, there was morphine, which is, I think, basically 100% processed natural opium. Heroin is a kind of a combo hybrid between synthetic and natural. And then fentanyl is just straight up like just made up. It's an analog. And it's way more potent than anything anyone had ever seen before when it came on the scene.

For those of you who don't know, it's a synthetic opioid. First, there was morphine, which is, I think, basically 100% processed natural opium. Heroin is a kind of a combo hybrid between synthetic and natural. And then fentanyl is just straight up like just made up. It's an analog. And it's way more potent than anything anyone had ever seen before when it came on the scene.

Right. And one of the things I just want to say that they messed around with molecularly to make fentanyl, they increased its fat solubility, which sounds like who cares? But that has two really important effects that make fentanyl what it is. One, it allows the drug to cross the blood-brain barrier faster, which means fentanyl has a much faster onset than heroin or morphine, right?

Right. And one of the things I just want to say that they messed around with molecularly to make fentanyl, they increased its fat solubility, which sounds like who cares? But that has two really important effects that make fentanyl what it is. One, it allows the drug to cross the blood-brain barrier faster, which means fentanyl has a much faster onset than heroin or morphine, right?