Chuck

Right. And one of the things I just want to say that they messed around with molecularly to make fentanyl, they increased its fat solubility, which sounds like who cares? But that has two really important effects that make fentanyl what it is. One, it allows the drug to cross the blood-brain barrier faster, which means fentanyl has a much faster onset than heroin or morphine, right?

It just hits you much faster. Right. And then it crosses back through the blood-brain barrier more quickly. So the duration of the high that you get lasts a shorter time. So just that one little tweak, fat solubility, made this drug what it is. Because faster onset makes it addictive. Shorter duration means that you need to do more.

It just hits you much faster. Right. And then it crosses back through the blood-brain barrier more quickly. So the duration of the high that you get lasts a shorter time. So just that one little tweak, fat solubility, made this drug what it is. Because faster onset makes it addictive. Shorter duration means that you need to do more.

It just hits you much faster. Right. And then it crosses back through the blood-brain barrier more quickly. So the duration of the high that you get lasts a shorter time. So just that one little tweak, fat solubility, made this drug what it is. Because faster onset makes it addictive. Shorter duration means that you need to do more.

Yeah, I think still today it's the most common opioid used for anesthesia during surgery. And that just sounds like madness when you're familiar with fentanyl, the street version. But in the hands of a really well-trained anesthesiologist with hospital-grade equipment, it's actually very safe. It's the fact that the stuff that you buy on the street has very uneven dosages.

Yeah, I think still today it's the most common opioid used for anesthesia during surgery. And that just sounds like madness when you're familiar with fentanyl, the street version. But in the hands of a really well-trained anesthesiologist with hospital-grade equipment, it's actually very safe. It's the fact that the stuff that you buy on the street has very uneven dosages.

Yeah, I think still today it's the most common opioid used for anesthesia during surgery. And that just sounds like madness when you're familiar with fentanyl, the street version. But in the hands of a really well-trained anesthesiologist with hospital-grade equipment, it's actually very safe. It's the fact that the stuff that you buy on the street has very uneven dosages.

It means that's why it's just so deadly because you're not a trained anesthesiologist. You're not using hospital grade equipment. You're shooting up something that some dude sold you. And it's just not it's just not trustworthy and it can kill you because it takes such a small amount to create a toxic dose.

It means that's why it's just so deadly because you're not a trained anesthesiologist. You're not using hospital grade equipment. You're shooting up something that some dude sold you. And it's just not it's just not trustworthy and it can kill you because it takes such a small amount to create a toxic dose.

It means that's why it's just so deadly because you're not a trained anesthesiologist. You're not using hospital grade equipment. You're shooting up something that some dude sold you. And it's just not it's just not trustworthy and it can kill you because it takes such a small amount to create a toxic dose.

Just a reminder, marijuana is Schedule I.

Just a reminder, marijuana is Schedule I.

Just a reminder, marijuana is Schedule I.

Yes. And there's different kinds, different analogs of fentanyl that everybody just kind of puts under the umbrella of fentanyl when you're talking about illicit fentanyl. But two of them that stand out that aren't actually illicit, but they're used in the drug market is carfentanil, which is used. There's no use for it in humans. They use it to sedate rhinoceroses and elephants.

Yes. And there's different kinds, different analogs of fentanyl that everybody just kind of puts under the umbrella of fentanyl when you're talking about illicit fentanyl. But two of them that stand out that aren't actually illicit, but they're used in the drug market is carfentanil, which is used. There's no use for it in humans. They use it to sedate rhinoceroses and elephants.

Yes. And there's different kinds, different analogs of fentanyl that everybody just kind of puts under the umbrella of fentanyl when you're talking about illicit fentanyl. But two of them that stand out that aren't actually illicit, but they're used in the drug market is carfentanil, which is used. There's no use for it in humans. They use it to sedate rhinoceroses and elephants.

And I think it's something like 10,000 times more potent than morphine. You can get that on the street apparently, although I think it's fairly rare. And then sufentanil is 5 to 10 times stronger than fentanyl. So if you – like people aren't like, yeah, it's carfentanil or sufentanil. You're talking about fentanyl.

And I think it's something like 10,000 times more potent than morphine. You can get that on the street apparently, although I think it's fairly rare. And then sufentanil is 5 to 10 times stronger than fentanyl. So if you – like people aren't like, yeah, it's carfentanil or sufentanil. You're talking about fentanyl.

And I think it's something like 10,000 times more potent than morphine. You can get that on the street apparently, although I think it's fairly rare. And then sufentanil is 5 to 10 times stronger than fentanyl. So if you – like people aren't like, yeah, it's carfentanil or sufentanil. You're talking about fentanyl.

Sure. The singer?