Cynthia Thurlow

speaker

1,574 appearances 4 recordings 3 series first heard Apr 2025 last heard 27 Apr

Cynthia Thurlow’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 2 in all, peaking in Apr 2026 with 1.

Appearances

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The Dylan Gemelli Podcast · Episode #116 Featuring Cynthia Thurlow PART 2! THE MENOPAUSE GUT: Balance Your Microbiome to Reclaim Your Health in Midlife and Beyond · 27 Apr 2026 podcast

And William is brilliant, as is Jeff, and just such nice down-to-earth clinicians and researchers.

So the immune system, as I mentioned, ages right along with us.

But what's interesting is that with this decline in estrogen, we start seeing immune system decline.

devolution, if you will.

So I mentioned that the immune system, immunosenescence, inflammation, all kind of correlates with these decline in hormones.

And estrogen and the immune system are intricately intertwined with one another as estrogen declines.

And I think everyone acknowledges that estrogen is an important hormone, actually for men and for women.

We start seeing more leaky gut.

If you think about the small intestinal lining, it's one cell layer thick.

And if you think about a brick and mortar analogy, estrogen is the mortar and the bricks.

And as estrogen is declining, we start seeing more tight junction opening and we will leak food particles into the bloodstream.

We'll trigger an immune response.

So this is when women will say, gosh, foods I used to eat just don't land the same way with me.

I'm suddenly sensitive to dairy or they get provocation of histamine responses and they suddenly start developing rashes or even allergic reactions to foods that had otherwise always been tolerated.

There's something called the thymus gland, and it's kind of by the time we get to be adults, it's kind of a fatty blob of tissue.

But what's interesting is in the immune system, we have these T helper cells.

We have a T helper one and T helper two.

And what happens to women in the setting of a decline in estrogen in particular, we start seeing more opportunistic infection.

We have less of a reaction to vaccine.

So when you go to CVS and they offer you a shingles vaccine, a flu vaccine and a pneumonia vaccine.

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