Cynthia Thurlow
speaker
1,574 appearances
4 recordings
3 series
first heard Apr 2025
last heard 27 Apr
Cynthia Thurlow’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Apr 2026 with 1.
Appearances
Not in every person.
Some women, about 25% still make enough testosterone.
But with those alterations, changes in the immune system, more susceptibility to stress.
Like one thing about women in middle age is that what you can get away with in terms of hormetic stress or just stress of life starts to shift.
So you don't cope quite as well when you're not sleeping seven, eight hours a night.
You don't cope quite as well with this really intense exercise.
So I usually use the example of
Orange Theory Fitness or CrossFit, if you think you can do that six days a week with no recovery, you're going to crash and burn in middle age.
I think for a lot of women, maybe they were doing a little bit of intermittent fasting at certain times during their cycle.
All of a sudden, like compressing their feeding window means they can't get enough protein in.
If they can't get enough protein in and they're not lifting regularly, they're going to get this unwinding of skeletal muscle.
And so sarcopenia is a real issue.
That also makes us lose insulin sensitivities.
Metabolic health piece, this weight loss resistance piece is never just one issue.
It is generally multiple issues that are contributing.
Not to mention the fact, as we're getting older, we produce less stomach acid.
Stomach acid is what helps break protein down into amino acids so it can be absorbed.
We generally also have less digestive enzymes, so we're not breaking down protein, fat, carbs.
So not able to absorb as much across that small intestinal lining.
And then as estrogen is declining, this is kind of one of those nerdy things.
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