Dave Mattingly

The NFL's championship game is Sunday at Levi's Stadium in Santa Clara, California, the home stadium of the San Francisco 49ers.

Big pharmaceutical companies who manufacture obesity drugs are pushing back against their competitors.

NPR's Sydney Lupkin says the latest skirmish is over a new version of Wegovi.

Wall Street is coming off a day of sharp losses.

The Dow, the S&P 500, and the Nasdaq all lost more than 1%.

I'm Dave Mattingly, NPR News in Washington.

Live from NPR News in Washington, I'm Dave Mattingly.

President Trump continues to ramp up pressure on Iran to scrap its nuclear ambitions ahead of tomorrow's scheduled talks in Oman.

NPR's Franco Ordonez reports on the president's latest remarks to NBC News.

President Trump's special envoy, Steve Witkoff, and Trump's son-in-law, Jared Kushner, among those scheduled to take part in the negotiations in Oman.

The talks were moved from Turkey at Tehran's request.

The U.S.

Supreme Court is allowing California to move forward with its new congressional map.

As Steve Futterman reports, state Republicans had challenged the redrawn map as unconstitutional, citing racial gerrymandering.

Authorities in Arizona and the FBI have yet to locate the mother of NBC Today show host Savannah Guthrie.

Investigators believe 84-year-old Nancy Guthrie was abducted from her home in the Tucson area.

She was last seen at her house five days ago.

The Guthrie family has released a video on social media asking for proof that their mother is still alive.

That's Savannah Guthrie speaking on the video in which she acknowledges the family has heard media reports about a possible ransom note.

The sheriff of Pima County says there's no evidence that the elder Guthrie was targeted.