David Friedberg

speaker
8,052 appearances 60 recordings 4 series first heard Apr 2024 last heard 21 Aug

David Friedberg’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 32 in all, peaking in Jan 2026 with 6.

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where the protein production, the production of these Yamanaka factors can be turned on and off by taking an antibiotic called doxycycline.
So the person that gets the delivery of this drug takes the antibiotic, turns on the production of these Yamanaka factors, and then theoretically their eye cells will de-age, will get youthful, and their vision will be restored.
So phase one clinical trials underway first time in human history, we're seeing Yamanaka factors being delivered into humans, literally the tip of the iceberg.
There are now over a dozen startups that are trying to deliver Yamanaka factors, which are these proteins or some other sort of protein that can actually reverse aging by restoring the epigenome and cells and make them young again.
So this is the beginning of a wave of what I think will be the most extraordinary revolution in human therapeutics, and ultimately could lead to, you know, some people would argue the fountain of youth.
Is this just a talk study?
So is it mechanism?
Yeah, well, they'll see results.
They'll see results, but they're gonna they're gonna keep dosing low, but you will see results.
It's going to be incredible.
By the way, a number of other folks that are gearing up for phase one using, if not the Yamanaka factors, other factors that they've identified or designed as an alternative to Yamanaka factors, again, to rejuvenate themselves.
And just to remind folks, the way this works is it was discovered that these proteins, when they go into a cell, they take all of those little markers that sit on top of your DNA that turn genes on and off.
And they create a system that causes them all to move to the right place.
So it resets the markers so that those cells will start to operate like they're supposed to when they were young again.
It's going to be incredible.
Arthritis.
Yep.
And by the way, when applied and if it's distributed in the skin, they've seen some results in monkeys where like wrinkles go away.
It like literally makes these cells all work youthful again.
And so a lot of the damage that happens over time is not damage to DNA.
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