Derek (More Plates More Dates)

Do push-ups first?

Yeah.

Oh, my God.

Thanks for having me.

I really appreciate the invite.

Yeah, I think at a basic level, it is the primary anabolic hormone men rely on for the sustainment or growth of muscle tissue, bone health, bone integrity, inhibiting degradation, indirectly through some of those pathways as well, insulin sensitivity, if you have insulin.

Worse in body composition, it becomes more difficult to handle glucose adequately.

Neurological health or the aromatization in the actual tissues themselves.

There's an array of things that are supported here.

critically by testosterone and its indirect metabolite activity as well through its aromatization to estrogen and I guess notably but often overlooked it's easy to forget but in adolescence the 5 alpha reduction to DHT so the conversion of testosterone to DHT is necessary for full maturation sexual differentiation to basically reach full adult male maturity and

There's a myriad of examples where FDHT is either too low via genetic predispositions or through different means than there is inhibited maturation.

And that's where you get into some of these more unique intersex cases.

But essentially, at a base level, this is the primary case.

Male, all but significantly impactful in females as well.

Hormone that is present at about 10x the concentrations in males and kind of differentiates them in terms of sexual identity and male characteristics.

Yeah, yeah.

And like, again, it's a non-exhaustive list that I just presented.

Like, the list extends beyond into erythropoiesis, the production of red blood cells, intratesticular testosterone production, absolutely critical for fertility as well.

And women...

All but not directly analogous intra-gonadally, but elsewhere in the body, the activity of testosterone is still necessary for a lot of the same things.