Dominic D'Agostino
๐ค SpeakerAppearances Over Time
Podcast Appearances
And the go-to would probably be the electrolyte salts just because you don't want to, for the average person, if you stay into that sweet spot of one to two millimolar,
If you elevate beta-hydroxybutyrate in the blood one millimolar, that represents a 10% increase of available energy to the brain.
We know that roughly speaking.
So all these calculations from the AV difference have been done.
So I think that's important.
Lactate is also something to consider.
I think lactate's an incredible molecule.
My early studies in 2004 and 2005, I think, was lactate.
But the ketones represented a more viable option and also had the anti-seizure effects that we had.
Plus, I was inspired by the work of George Cahill and Dr. Veach and Theodore Van Italy.
And then I got steered towards beta-hydroxybutyrate.
But I think an important message is that formulation is the key.
So you have beta-hydroxybutyrate, you have lactate, you have MCTs cross the blood-brain barrier.
So it's a type of fat that actually can cross the blood-brain barrier.
I think MCTs are great.
I use a coffee creamer called Keto Brains.
It's like alpha-GPC, MCT, theanine.
It's a mixture of combinations of things.
But when you combine a ketone salt with MCT, then you have a formulation that stimulates your own ketone production while you're delivering an exogenous ketone.
And if it's a racemic DL-beta-hydroxybutyrate-like keto start, then you have a sustained ketone delivery system for half of the day.