Dominic D'Agostino

No, it's not.

And my mentor, Dr. J. Dean, our lab is like a museum.

So we have all the historic pictures on there.

And there's a guy that wrote a book and his name was Fred Baer.

He was a French physiologist.

He did a lot of seminal studies well over a hundred years ago in the 1800s showing that you could give animals, they called it caissons disease too.

So that could, when you go down in like chambers, when you're building a bridge, you're under high pressure oxygen or high atmospheric effects.

So yeah, I would say about 150 years ago, we realized that oxygen was a stimulant.

We didn't know why.

And then with military diving, then you have the problem of averting oxygen seizures.

And there's a number of people in the Navy.

Frank Butler comes to mind, Claude Pianidosi, Richard Moon.

There's a network at Duke University, which did a lot of the seminal studies.

And they established the dive tables for preventing oxygen toxicity seizures, nitrogen narcosis, high pressure nervous syndrome.

So these are all things that you have to avert when you're diving, depending on what kind of diving you're doing.

Yeah.

I kind of went to them, or they came to me because I had specialized knowledge, but I wrote grants to really delve into, it's unknown why these seizures occur, but it gives us a lot of insight into the brain to understand it from a redox effect, from a neuropharmacology effect.

So the grants that I had were literally called Investigating the Cellular and Molecular Mechanisms of CNS Oxygen Toxicity.

And they gave me

Unlike the NIH, they gave me, I had a lot of tools to play with that were really expensive that we got through what's called a DOD DURUP grant.