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Dr. Abraham Morgentaler

๐Ÿ‘ค Speaker
944 total appearances

Appearances Over Time

Podcast Appearances

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

The deep part of our brain that's also involved with sexual behavior, we still call the reptilian portion of our brain. And we call it that because some of the old parts of the brain are conserved. You know, the processes are identical or almost identical, going back to earlier vertebrates in evolution, like the reptiles.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So having done that research was the only reason I ever conceived of testosterone. All I knew of testosterone was it's dangerous. If somebody has bad prostate cancer, we lower it. Castration was a common procedure I did as a junior resident. And then the LHRH agonist started coming in towards the end of my residency. We started using that. But it occurred to me that maybe men...

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So having done that research was the only reason I ever conceived of testosterone. All I knew of testosterone was it's dangerous. If somebody has bad prostate cancer, we lower it. Castration was a common procedure I did as a junior resident. And then the LHRH agonist started coming in towards the end of my residency. We started using that. But it occurred to me that maybe men...

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So having done that research was the only reason I ever conceived of testosterone. All I knew of testosterone was it's dangerous. If somebody has bad prostate cancer, we lower it. Castration was a common procedure I did as a junior resident. And then the LHRH agonist started coming in towards the end of my residency. We started using that. But it occurred to me that maybe men...

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

were like lizards. And I took a few of these guys who were pretty desperate, and without knowing what the effect would be, I just gave them some testosterone. I told them, you know, there's a risk of prostate cancer, and they were willing to take whatever risk it was. And you know what? It worked for them. And it worked for them sexually, and it worked for them in ways that I hadn't anticipated.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

were like lizards. And I took a few of these guys who were pretty desperate, and without knowing what the effect would be, I just gave them some testosterone. I told them, you know, there's a risk of prostate cancer, and they were willing to take whatever risk it was. And you know what? It worked for them. And it worked for them sexually, and it worked for them in ways that I hadn't anticipated.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

were like lizards. And I took a few of these guys who were pretty desperate, and without knowing what the effect would be, I just gave them some testosterone. I told them, you know, there's a risk of prostate cancer, and they were willing to take whatever risk it was. And you know what? It worked for them. And it worked for them sexually, and it worked for them in ways that I hadn't anticipated.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

And these men would tell me stories like that they have more patience to play with their small children, that their wife likes them more, that they wake up in the morning with optimism for their day, which they hadn't had in many years. And it was rather remarkable. And so I stuck with it, but I monitored the prostates extremely carefully.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

And these men would tell me stories like that they have more patience to play with their small children, that their wife likes them more, that they wake up in the morning with optimism for their day, which they hadn't had in many years. And it was rather remarkable. And so I stuck with it, but I monitored the prostates extremely carefully.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

And these men would tell me stories like that they have more patience to play with their small children, that their wife likes them more, that they wake up in the morning with optimism for their day, which they hadn't had in many years. And it was rather remarkable. And so I stuck with it, but I monitored the prostates extremely carefully.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

And before too, too long, I actually started doing biopsies of the prostate just to protect myself and my patients to make sure that they didn't have prostate cancer that might grow. And this was prior to the PSA or PSA was already... PSA was relatively new, but it was there. So... You know, in academic centers, we were already using PSA. But as you know, PSA isn't perfect.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

And before too, too long, I actually started doing biopsies of the prostate just to protect myself and my patients to make sure that they didn't have prostate cancer that might grow. And this was prior to the PSA or PSA was already... PSA was relatively new, but it was there. So... You know, in academic centers, we were already using PSA. But as you know, PSA isn't perfect.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

And before too, too long, I actually started doing biopsies of the prostate just to protect myself and my patients to make sure that they didn't have prostate cancer that might grow. And this was prior to the PSA or PSA was already... PSA was relatively new, but it was there. So... You know, in academic centers, we were already using PSA. But as you know, PSA isn't perfect.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So I was doing biopsies in prostates of men with normal PSA, normal digital rectal exam, only because their testosterone was low. And my first paper relevant to this to the prostate cancer story was actually the first piece of evidence that the testosterone and prostate cancer story wasn't correct.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So I was doing biopsies in prostates of men with normal PSA, normal digital rectal exam, only because their testosterone was low. And my first paper relevant to this to the prostate cancer story was actually the first piece of evidence that the testosterone and prostate cancer story wasn't correct.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So I was doing biopsies in prostates of men with normal PSA, normal digital rectal exam, only because their testosterone was low. And my first paper relevant to this to the prostate cancer story was actually the first piece of evidence that the testosterone and prostate cancer story wasn't correct.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

Because not only was it believed that high testosterone caused prostate cancer and made it grow quickly, it was also believed that if you had low levels, you would never get prostate cancer. As a resident, we heard, eunuchs never get prostate cancer. It's not exactly true, and one has to wonder, how do people know so much about eunuchs and prostate cancer?

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

Because not only was it believed that high testosterone caused prostate cancer and made it grow quickly, it was also believed that if you had low levels, you would never get prostate cancer. As a resident, we heard, eunuchs never get prostate cancer. It's not exactly true, and one has to wonder, how do people know so much about eunuchs and prostate cancer?

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

Because not only was it believed that high testosterone caused prostate cancer and made it grow quickly, it was also believed that if you had low levels, you would never get prostate cancer. As a resident, we heard, eunuchs never get prostate cancer. It's not exactly true, and one has to wonder, how do people know so much about eunuchs and prostate cancer?

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

How many doctors were around who had a large population of eunuchs that they would follow for 50 years or so until they were in their 70s or 80s and decided, yep, there's no cancer? Nobody. I mean, it's not real, but that was a story. And so these were men that we were biopsying before testosterone. And the only reason we were biopsying them was because they had low testosterone.