Dr. Abraham Morgentaler
👤 PersonAppearances Over Time
Podcast Appearances
And I'm thinking, I read through it. And the last sentence, the last sentence of the article says, testosterone injections activate prostate cancer. And I was sick to my stomach. I was awful. My hands were sweating. And I had visions of the Harvard police coming and arresting me then and there.
And I'm thinking, I read through it. And the last sentence, the last sentence of the article says, testosterone injections activate prostate cancer. And I was sick to my stomach. I was awful. My hands were sweating. And I had visions of the Harvard police coming and arresting me then and there.
And it being a big Boston Globe front page story that my kids would see, you know, the Harvard doctor like arrested for, you know, ethical malpractice by giving testosterone. And so I forced myself to reread the article. And just wrote down a few basic questions. How many men did he treat? For how long?
And it being a big Boston Globe front page story that my kids would see, you know, the Harvard doctor like arrested for, you know, ethical malpractice by giving testosterone. And so I forced myself to reread the article. And just wrote down a few basic questions. How many men did he treat? For how long?
And it turned out that the number of men he had treated, most of this was about the guys he'd castrated. The number of men he treated was only three. Only three. Of the three he had treated, he only actually gave any information about two of them. One of those men had already been castrated, which today we know is a special case.
And it turned out that the number of men he had treated, most of this was about the guys he'd castrated. The number of men he treated was only three. Only three. Of the three he had treated, he only actually gave any information about two of them. One of those men had already been castrated, which today we know is a special case.
So this whole idea that testosterone causes, the general concept makes prostate cancer grow, or as Huggins said, activated, was based on one guy who received testosterone for only 18 days. And his curve is uninterpretable. Goes up and down, up and down, before and after testosterone. It was amazing.
So this whole idea that testosterone causes, the general concept makes prostate cancer grow, or as Huggins said, activated, was based on one guy who received testosterone for only 18 days. And his curve is uninterpretable. Goes up and down, up and down, before and after testosterone. It was amazing.
Acid phosphatase.
Acid phosphatase.
Yeah.
Yeah.
Yeah. What can we learn from that? Yeah. I'm so glad that you're underscoring this point because, you know, I've done research for 50 years since I was 19. Since yesterday. And all different kinds, right? Like randomized trials, pharmacokinetic studies, animal studies, basic science studies. My greatest discovery is
Yeah. What can we learn from that? Yeah. I'm so glad that you're underscoring this point because, you know, I've done research for 50 years since I was 19. Since yesterday. And all different kinds, right? Like randomized trials, pharmacokinetic studies, animal studies, basic science studies. My greatest discovery is
was actually figuring out, finding out that Huggins based this whole thing on one patient. And he was wrong about it. There was a misinterpretation of that information. And that's the basis why people around the world have learned for 80 years, have been told that testosterone... activates prostate cancer, and later it switched.
was actually figuring out, finding out that Huggins based this whole thing on one patient. And he was wrong about it. There was a misinterpretation of that information. And that's the basis why people around the world have learned for 80 years, have been told that testosterone... activates prostate cancer, and later it switched.
Huggins never said this, but people started to believe that testosterone actually caused prostate cancer, which it doesn't do either. There's no evidence for that, none, zero. Nor does it make the cancer any worse, unless, here's the thing, unless you're already castrated, which only happens if you've already been treated for advanced prostate cancer. And that's where people have messed up.
Huggins never said this, but people started to believe that testosterone actually caused prostate cancer, which it doesn't do either. There's no evidence for that, none, zero. Nor does it make the cancer any worse, unless, here's the thing, unless you're already castrated, which only happens if you've already been treated for advanced prostate cancer. And that's where people have messed up.
You know, so the field has moved. I'm proud to have been involved in some of that. But man, it's hard. I've been railing at this point for so long. I've been debating on stage at the national urology meetings, prostate cancer stuff for so long. And that's probably not a comfortable place to be. Well, I have to tell you, there's a part of me that enjoys that. I do.
You know, so the field has moved. I'm proud to have been involved in some of that. But man, it's hard. I've been railing at this point for so long. I've been debating on stage at the national urology meetings, prostate cancer stuff for so long. And that's probably not a comfortable place to be. Well, I have to tell you, there's a part of me that enjoys that. I do.