Dr. Abud Bakri
π€ SpeakerAppearances Over Time
Podcast Appearances
Because if you think about it, the better way to think about weight loss, it's the calculation your brain does every single day with all the different hormones and peptides that are made from the gut, the GIP, GLP, glucagon, insulin, testosterone, estrogen, all these things can kind of modulate.
And there's this thing called a set point theory or settling points.
And they integrate, should I eat or not eat, right?
So the GLP-1 is a giant signal to the brain of don't eat.
So we're modulating this pathway.
What happens to all these young kids that are 18, 19 years old on five milligrams of Ritatrutide that have lost 30, 40 pounds?
Are they going to have to be on that for life now to maintain that weight?
Can I ask you about that?
Yeah, like the effects for like, let's say, a 60-year-old pre-diabetic diabetic on Alzheimer's disease seems to be potentially positive.
I think the study last year didn't show a good signal on Alzheimer's prevention.
But we know diabetes and cardiomyobolic disease speeds up that transition.
So controlling insulin dynamics might be beneficial there.
And obesity is not great for Alzheimer's risk.
The question is, what about for like these cognitive effects?
Is the effect happening from the drug itself?
Is it from misuse of the drug, too high of a dose?
You're not getting enough electrolytes.
You're not getting enough micronutrients, macronutrients.
You know, your blood sugar is low.
Because a lot of these patients, the way we approach it is,