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Dr. Abud Bakri

πŸ‘€ Speaker
1676 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Because if you think about it, the better way to think about weight loss, it's the calculation your brain does every single day with all the different hormones and peptides that are made from the gut, the GIP, GLP, glucagon, insulin, testosterone, estrogen, all these things can kind of modulate.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And there's this thing called a set point theory or settling points.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And they integrate, should I eat or not eat, right?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So the GLP-1 is a giant signal to the brain of don't eat.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So we're modulating this pathway.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

What happens to all these young kids that are 18, 19 years old on five milligrams of Ritatrutide that have lost 30, 40 pounds?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Are they going to have to be on that for life now to maintain that weight?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Can I ask you about that?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Yeah, like the effects for like, let's say, a 60-year-old pre-diabetic diabetic on Alzheimer's disease seems to be potentially positive.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

I think the study last year didn't show a good signal on Alzheimer's prevention.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

But we know diabetes and cardiomyobolic disease speeds up that transition.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So controlling insulin dynamics might be beneficial there.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And obesity is not great for Alzheimer's risk.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

The question is, what about for like these cognitive effects?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Is the effect happening from the drug itself?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Is it from misuse of the drug, too high of a dose?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

You're not getting enough electrolytes.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

You're not getting enough micronutrients, macronutrients.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

You know, your blood sugar is low.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Because a lot of these patients, the way we approach it is,