Dr. Adeel Khan
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Podcast Appearances
And so basically these 12, let's call them the 12 hallmarks. They actually underlie not just aging, which is, you know, arguably the most complex chronic disease. They underlie all chronic diseases from stroke, from heart disease to asthma, to dementia, to cancer even, and just components of that that are overlying. And a lot of them are metabolic in nature.
And so basically these 12, let's call them the 12 hallmarks. They actually underlie not just aging, which is, you know, arguably the most complex chronic disease. They underlie all chronic diseases from stroke, from heart disease to asthma, to dementia, to cancer even, and just components of that that are overlying. And a lot of them are metabolic in nature.
And so that's why these stem cells have this ability to restore metabolic health because of that mitochondrial DNA transfer and helping to repair the mitochondria through mitophagy. And then, of course, the mitochondria are the ones that help to regulate metabolism, right?
And so that's why these stem cells have this ability to restore metabolic health because of that mitochondrial DNA transfer and helping to repair the mitochondria through mitophagy. And then, of course, the mitochondria are the ones that help to regulate metabolism, right?
That's where they have, that's where your, when you eat food and your body has to process it, it has to go through your mitochondria to produce energy. And if your mitochondria aren't working properly, which is what happens to everyone with aging and chronic disease, then guess what? Your metabolism is messed up.
That's where they have, that's where your, when you eat food and your body has to process it, it has to go through your mitochondria to produce energy. And if your mitochondria aren't working properly, which is what happens to everyone with aging and chronic disease, then guess what? Your metabolism is messed up.
And that's why metabolic disease is really the root cause of so many different problems. And that's why they call, you know, dementia type 3 diabetes. And all this other stuff, right? Because a lot of them are metabolic in nature. And if you can restore metabolic health, which stem cells can do, then that's why you can treat so many chronic diseases. And that's number one.
And that's why metabolic disease is really the root cause of so many different problems. And that's why they call, you know, dementia type 3 diabetes. And all this other stuff, right? Because a lot of them are metabolic in nature. And if you can restore metabolic health, which stem cells can do, then that's why you can treat so many chronic diseases. And that's number one.
And number two, the other beauty of these stem cells is their ability to regulate your immune system. So this is called immunomodulation. That's the medical term, but that just basically means we're shifting your body from a pro-inflammatory state to an anti-inflammatory state. So this is called immunomodulation, which is reprogramming your immune cells, specifically your macrophages.
And number two, the other beauty of these stem cells is their ability to regulate your immune system. So this is called immunomodulation. That's the medical term, but that just basically means we're shifting your body from a pro-inflammatory state to an anti-inflammatory state. So this is called immunomodulation, which is reprogramming your immune cells, specifically your macrophages.
And if there's one cell that you need to understand, it's your macrophages. They're my favorite cell in the body.
And if there's one cell that you need to understand, it's your macrophages. They're my favorite cell in the body.
Exactly. So they're like your little Pac-Man controlling and surveilling and making sure the bad guys don't get in and they eat the bad guys when they're around. They take them away and they'll dispose of them. But what happens to a lot of Pac-Men or police officers, I like to call them, is they get fat and tired. And then they start eating too many donuts and they can't do their job anymore.
Exactly. So they're like your little Pac-Man controlling and surveilling and making sure the bad guys don't get in and they eat the bad guys when they're around. They take them away and they'll dispose of them. But what happens to a lot of Pac-Men or police officers, I like to call them, is they get fat and tired. And then they start eating too many donuts and they can't do their job anymore.
And this is actually called lipid associated macrophages or LAMs. And so they accumulate fat and lipid perioxidation inside of the macrophage, and then they can't do their job anymore, and their job is so important. And then they start releasing the wrong signals. So the macrophages start releasing pro-inflammatory signals, and then that causes the cycle of chronic inflammation.
And this is actually called lipid associated macrophages or LAMs. And so they accumulate fat and lipid perioxidation inside of the macrophage, and then they can't do their job anymore, and their job is so important. And then they start releasing the wrong signals. So the macrophages start releasing pro-inflammatory signals, and then that causes the cycle of chronic inflammation.
And that's really the root, as we know, of so many disease processes. And that's why if you can treat chronic inflammation, you can treat so many different chronic diseases. And that's why these IV mu cells have so much potential. And even with IV,
And that's really the root, as we know, of so many disease processes. And that's why if you can treat chronic inflammation, you can treat so many different chronic diseases. And that's why these IV mu cells have so much potential. And even with IV,
let's call it the first generation even with the iv you know first generation stem cells there are clinical trials that are published showing that inflammatory bowel disease can get into remission that rheumatoid arthritis can get into remission it's just the dosing is quite high and people need a lot of frequency of those but with the new cells you can get obviously you can get a lot better results but it's the same principle which is you're just regulating the immune system
let's call it the first generation even with the iv you know first generation stem cells there are clinical trials that are published showing that inflammatory bowel disease can get into remission that rheumatoid arthritis can get into remission it's just the dosing is quite high and people need a lot of frequency of those but with the new cells you can get obviously you can get a lot better results but it's the same principle which is you're just regulating the immune system