Dr. Andy Galpin

what I just described, some of these sleep-wake abnormalities, with the main effects probably being correction of that excitotoxicity issue and some of the GABA and other glutamate problems that we have just described. Probably the most famous study in this area is called the HIT Heads Trial. I believe this came out in 2024, actually, so pretty recent. It was a pilot randomized controlled trial.

what I just described, some of these sleep-wake abnormalities, with the main effects probably being correction of that excitotoxicity issue and some of the GABA and other glutamate problems that we have just described. Probably the most famous study in this area is called the HIT Heads Trial. I believe this came out in 2024, actually, so pretty recent. It was a pilot randomized controlled trial.

They had, I think, like 10 to 35-year-olds in there, so teens, preteens, all the way up to normal age. And they followed them for three weeks or 21 days post-injury. And this was really cool. They had, I think, five arms in this study. So some of the participants just got a placebo. And then they broke up the rest of the intervention by dosage. So they got 15 grams a day, 30 grams, 45, or even 54.

They had, I think, like 10 to 35-year-olds in there, so teens, preteens, all the way up to normal age. And they followed them for three weeks or 21 days post-injury. And this was really cool. They had, I think, five arms in this study. So some of the participants just got a placebo. And then they broke up the rest of the intervention by dosage. So they got 15 grams a day, 30 grams, 45, or even 54.

I'm not sure why it's only 55. But they wanted to see, is there an effect at all compared to placebo? And if there is, what's the optimal dosage? And they gave them five different dosages from low dose to more moderate to pretty high and scaled all the way up. And one of the things that they found was a pretty clear dose response such that the most improvements were found in that 54 grams per day.

I'm not sure why it's only 55. But they wanted to see, is there an effect at all compared to placebo? And if there is, what's the optimal dosage? And they gave them five different dosages from low dose to more moderate to pretty high and scaled all the way up. And one of the things that they found was a pretty clear dose response such that the most improvements were found in that 54 grams per day.

decreased symptoms of concussions, faster and better return to baseline. There were not benefits actually in what was called processing speed. So that had been shown in some of the earlier studies we talked about, but they didn't find that here for whatever reason. But they had all those other benefits.

decreased symptoms of concussions, faster and better return to baseline. There were not benefits actually in what was called processing speed. So that had been shown in some of the earlier studies we talked about, but they didn't find that here for whatever reason. But they had all those other benefits.

One more time, highlights the fact that not every supplement, not every food, not every nutrient fixes every problem. Okay, so benefits here in the concussion symptoms, but not necessarily the processing speed. But the effects one more time were dose dependent. And one more time, like we keep bringing up, there was no adverse effects reported.

One more time, highlights the fact that not every supplement, not every food, not every nutrient fixes every problem. Okay, so benefits here in the concussion symptoms, but not necessarily the processing speed. But the effects one more time were dose dependent. And one more time, like we keep bringing up, there was no adverse effects reported.

The data that we currently have suggests up to 55 or 54 grams per day, more specifically, is a dosage. You would want to make sure you're at that higher dosage past injury. You can be at a much smaller one. Just honestly make sure your protein intake is high enough. You can use whatever number you like. We've talked many times, though.

The data that we currently have suggests up to 55 or 54 grams per day, more specifically, is a dosage. You would want to make sure you're at that higher dosage past injury. You can be at a much smaller one. Just honestly make sure your protein intake is high enough. You can use whatever number you like. We've talked many times, though.

I personally like one gram of protein per pound of body weight. If you're at that, you're probably getting enough BCAAs at baseline, and then we would go to only this higher dose post-brain injury. To break this down food-wise... BCAAs, it's protein, it's dairy products, it's meat and poultry. Most meat's gonna be three to four grams of BCAAs per 100 grams of serving.

I personally like one gram of protein per pound of body weight. If you're at that, you're probably getting enough BCAAs at baseline, and then we would go to only this higher dose post-brain injury. To break this down food-wise... BCAAs, it's protein, it's dairy products, it's meat and poultry. Most meat's gonna be three to four grams of BCAAs per 100 grams of serving.

And so similar math that we've done before, okay? This is gonna result in you having to have like 40 or 50 ounces of meat per day. Not something you need baseline, but in these small cases, again, I don't want you to feel like I'm pushing you to supplements, but it is just significantly easier here for small times and for specific scenarios of a brain injury to go to supplementation here.

And so similar math that we've done before, okay? This is gonna result in you having to have like 40 or 50 ounces of meat per day. Not something you need baseline, but in these small cases, again, I don't want you to feel like I'm pushing you to supplements, but it is just significantly easier here for small times and for specific scenarios of a brain injury to go to supplementation here.

Our next micronutrient is magnesium. Oh my goodness, could I go on and on and on about the physiological benefits of magnesium. It is involved in well over 600 reactions in your body from cell signaling, vascular function, ATP production, protein synthesis, neuroplasticity, learning, memory, and I could basically think of anything that happens in your body and magnesium's central to that.

Our next micronutrient is magnesium. Oh my goodness, could I go on and on and on about the physiological benefits of magnesium. It is involved in well over 600 reactions in your body from cell signaling, vascular function, ATP production, protein synthesis, neuroplasticity, learning, memory, and I could basically think of anything that happens in your body and magnesium's central to that.

I don't have to draw this out then. It's pretty easy for you to assume this is going to be an important role in your brain pre and post-injury.

I don't have to draw this out then. It's pretty easy for you to assume this is going to be an important role in your brain pre and post-injury.