Dr. Andy Galpin

We also have very strong data if you are deficient in magnesium, you have associations with a host of comorbidities, health conditions, type two diabetes, metabolic syndrome, hypertension, headaches is another common one, migraines, heart disease, so on and so forth. We know that it probably inhibits receptors that are directly targets

We also have very strong data if you are deficient in magnesium, you have associations with a host of comorbidities, health conditions, type two diabetes, metabolic syndrome, hypertension, headaches is another common one, migraines, heart disease, so on and so forth. We know that it probably inhibits receptors that are directly targets

of antidepressants as well, and is a strong contributor to that brain excitotoxicity after injury. So you do not want to be deficient in magnesium. You can listen to, read almost anything in the sports performance realm, and you will see magnesium as a top tier supplementation. It is really robust and a strong line of evidence and recommended by, again, many people in this field.

of antidepressants as well, and is a strong contributor to that brain excitotoxicity after injury. So you do not want to be deficient in magnesium. You can listen to, read almost anything in the sports performance realm, and you will see magnesium as a top tier supplementation. It is really robust and a strong line of evidence and recommended by, again, many people in this field.

But surprisingly, the SOE is only three here. There's a well-documented drop in magnesium, especially in your central neurons after a TBI. And the extent of that drop is associated with the severity of the injury and the level of behavioral disturbances. So not only the injury, but your symptoms as well. Animal and human research here from the animals, it's associated with edema.

But surprisingly, the SOE is only three here. There's a well-documented drop in magnesium, especially in your central neurons after a TBI. And the extent of that drop is associated with the severity of the injury and the level of behavioral disturbances. So not only the injury, but your symptoms as well. Animal and human research here from the animals, it's associated with edema.

brain and blood concentrations, calcium problems, like we talked about earlier. These are going to result in those behavioral modifications, memory, cognitive function, spatial and working memory, and so on and so forth. From the actual human stuff, Couple of studies that are worth drawing attention to here.

brain and blood concentrations, calcium problems, like we talked about earlier. These are going to result in those behavioral modifications, memory, cognitive function, spatial and working memory, and so on and so forth. From the actual human stuff, Couple of studies that are worth drawing attention to here.

One looked at acute TBIs in kids and saw a significant reduction in post-concussion severity scores 48 hours after the injury when they used 400 milligrams of magnesium twice per day. Now, another study used a similar design and didn't find a benefit, but this was actually using magnesium from an IV for five days.

One looked at acute TBIs in kids and saw a significant reduction in post-concussion severity scores 48 hours after the injury when they used 400 milligrams of magnesium twice per day. Now, another study used a similar design and didn't find a benefit, but this was actually using magnesium from an IV for five days.

Now, no one really actually knows why this one trial worked and the other one didn't. The obvious thought is maybe there's something that happens when you ingest it through your stomach that aids in digestion or makes it more bioavailable. But when you took it with the IV, it didn't. To me, that's honestly not a great answer. But I don't have any other reason to think that that happened.

Now, no one really actually knows why this one trial worked and the other one didn't. The obvious thought is maybe there's something that happens when you ingest it through your stomach that aids in digestion or makes it more bioavailable. But when you took it with the IV, it didn't. To me, that's honestly not a great answer. But I don't have any other reason to think that that happened.

So really honestly, to summarize here, it is very, very safe. It's very little harm. It has so many other health and performance related benefits. There's so many health consequences that are associated with magnesium deficiency. It helps with symptoms and behaviors that are hallmarks of TBI, like we've talked about.

So really honestly, to summarize here, it is very, very safe. It's very little harm. It has so many other health and performance related benefits. There's so many health consequences that are associated with magnesium deficiency. It helps with symptoms and behaviors that are hallmarks of TBI, like we've talked about.

So I know the SOE is technically three, but personally it's about as high on the list as I could think one supplement could be. The dosages we described one more time, 400 milligrams per day. The timing doesn't matter. You'll want to have some in there pre as well as post injury, and you could take it at any point in the day.

So I know the SOE is technically three, but personally it's about as high on the list as I could think one supplement could be. The dosages we described one more time, 400 milligrams per day. The timing doesn't matter. You'll want to have some in there pre as well as post injury, and you could take it at any point in the day.

Now, depending on the type or form that you use, you might want to take it later in the evening. Some people report, and depending on the type, magnesium helps you fall asleep. I personally feel no effect at all, but most people do. I still then take my magnesium at night just because, just in case. There's all kinds of forms.

Now, depending on the type or form that you use, you might want to take it later in the evening. Some people report, and depending on the type, magnesium helps you fall asleep. I personally feel no effect at all, but most people do. I still then take my magnesium at night just because, just in case. There's all kinds of forms.

You've heard of magnesium threonate at this point, bisglycinate, malate. And right now, I don't know of any compelling evidence to suggest one of those forms is any better than another. Obviously, magnesium threonate has become more popular recently. And that may turn out to be more effective. It may not. I'm not sure. There's just not enough data for us to have really an answer at this point.

You've heard of magnesium threonate at this point, bisglycinate, malate. And right now, I don't know of any compelling evidence to suggest one of those forms is any better than another. Obviously, magnesium threonate has become more popular recently. And that may turn out to be more effective. It may not. I'm not sure. There's just not enough data for us to have really an answer at this point.