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Dr. Andy Galpin

๐Ÿ‘ค Speaker
9972 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

The patella tendon inserts on the front of the lower leg bone, which causes the lower leg bone to lift up and for your lower leg to extend.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

That quickly is how muscles work and how they actually cause human movement.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

It's through, one, the activation of the muscle, two, the contraction of the muscle, and then three, the muscle pulling on connective tissue, which makes bones move.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Now, the amount of muscle fibers you've got in each muscle varies pretty highly, and it's somewhere in the neighborhood of 1,000 to 300,000 individual fibers.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Interestingly, this number will double during the first few months of your life and then basically stabilize by the time you reach adulthood.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Now, as I mentioned, you've got somewhere between 100,000 and 300,000 fibers per muscle.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

One example, the biceps brachii has been shown to have about 250,000 muscle fibers.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

And so if you ran some quick math there, that would mean most of us probably have somewhere in the neighborhood of between 125 to 250 million muscle fibers throughout our entire body.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

And these fibers are extraordinarily unique in all of biology.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

For a couple of reasons.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Number one, they are absolutely huge.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

They are some of the biggest cells by volume in all of biology.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

It is common to have a muscle fiber that is up to two to three centimeters long.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

And in fact, many have been shown to be up to 10 centimeters or so long.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Think about the sartorius muscle, this muscle that goes from kind of the inside of your hip bone, that front side there, and goes all the way to the inside of your knee.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

It is theorized, and some folks will say in physiology lore, that you can have a single muscle fiber that runs the entire length of that.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

I don't actually know whether or not that's true, but it would not be rare to see a fiber that is, again, four to five to up to six inches long, which is enormous in terms of the width.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Same kind of idea.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

You'll see these things as extremely large, right?

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Somewhere between four to five micrometers in terms of cross-sectional areas, micrometer squared.