Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
Look at that spectrum, right?
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
Almost a 65-year spectrum.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
And within that, 175,000 people or so died.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
So if it held up against 15,000, then it held up against 150,000, and now it's holding up against 750,000.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
I just don't know how much more evidence one would need to see to believe not only in this as an actual finding,
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
But the relative risk ratio seems to be lining up across all these studies as pretty similar.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
And so what they found in this, again, same idea.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
They found no reduced benefit of extreme fitness.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
In other words, the higher the VO2 max, just the higher the risk reduction.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
There seemed to be no upper limit there.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
And in addition, what they found was a couple of metrics.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
So if you take into account what are called the comorbidities, and so you look at things like diabetes.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
Diabetes in this particular study took their risk factor from 1 to 1.34.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
So that's a big deal.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
However, going from the highest fitness level to the next highest fitness level,
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
represented an increase of risk of 1.66.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
So again, I'm not saying that diabetes is okay or anything like that.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
Again, I'm not a medical doctor and I don't do really anything with disease, but just look how staggering this is.
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
And in fact, if you run this all the way out, examples in this paper and here I'm looking at
Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
a figure two, by the way, in case you want to go look yourself.