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Dr. Andy Galpin

๐Ÿ‘ค Speaker
10279 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

Another thing that differentiates the skeletal from the cardiac tissue is how and how long they contract.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

In skeletal muscle, we actually want the ability to do what's called summation to reach tetany.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And so what happens is the muscle fibers in, say, your biceps brachii will contract with that electrical potential.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And then actually almost before it gets all the way back to baseline, it will contract again.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And then it'll contract again and contract again.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And so those mini contractions start to stack on top of each other or summate.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And in fact, if you do that long enough, you can reach what is called full tetany.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

Think of this as a muscle cramp.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

So this is the muscle fibers themselves contracting permanently instead of doing this kind of on-off, on-off rhythm.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

Cardiac tissue doesn't do that, and I think you could probably imagine why.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

It would be a very bad thing for you to reach tetany of your heart.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

Remember, when we first started talking about the anatomy of your heart,

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

The primary job of the heart is to move blood from the atria, or the top of the heart, to the ventricles in the bottom, and then move that out to the body.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

So if this thing were to reach tetany, blood wouldn't move anywhere.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

You wouldn't be able to circulate any blood throughout your body, and of course you would die.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

So while it's okay to have a cramp in your calf and it's painful and it's annoying and it's all those things, having a cramp in your heart would be far worse.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And so your body hedges against that.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

And what it says is, all right, if I have this extremely fast, what's called refractory time in skeletal muscle, it's the ability to kind of contract multiple times within a single muscle fiber.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

I want to extend the time of contraction in the cardiac tissue so that I don't have that repeat in summation.

Huberman Lab
Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

So in addition to not wanting tetany, you also need to allow time for blood to fill up the ventricles.