Dr. Aseem Malhotra
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Okay, interesting.
But what was surprising was there was an inverse association with LDL cholesterol and all-cause mortality.
In other ways, statistically, if you're over 60, the higher LDL, the less likely you are to die.
So what's the reasoning for that?
Well, something that's been forgotten or missed or not discussed.
Cholesterol has a very vital role in many functions in the body, including the brain, hormone production, but also the immune system.
And it's likely that that's where the protective benefit comes because older people are more vulnerable to dying from infections.
And we also know there is an association, I'll use this word, an association, right?
Can't say it's definitely causal, between low cholesterol and cancer.
Again, it's probably related to the immune system.
So let me push back on that.
So we counted for that.
And we found, actually, no, when you count time lag, you go back 5 or 10 years.
No, it's not.
That does happen.
But no, independently, it does seem to be an issue.
It's a chronic inflammatory process exacerbated by metabolic risk factors or insulin resistance.
And I wrote an editorial- Metabolic risk factors, by that you mean-
Problems with your blood sugar and insulin.
And pre-diabetes.