Dr. Ben Bikman

No.

No, in fact, that's why with the slow insulin resistance, the reversal of that, like over the 90 days in the type 2 diabetic patients that we had in our published case series, that would have been, not that we measured this, but it would have been because of a shrinking of the fat cell.

Now, let's say they grow those fat cells again, the same problems will come back, right?

So whatever intervention, one of the problems I have with diet, whatever the intervention is, low carb or calorie restricted, whatever, people will complain and they'll say, well, but it's only short term.

Yeah, of course it is.

Whatever a person has done to reverse their metabolic problems will only persist as long as they adhere to those changes.

The more they go back to their old habits, the more the same consequences will return because it was those old habits that caused it.

It can only go through hypertrophy.

Yeah, that's a great question.

So visceral adipocytes are more responsive to the lipolytic signal, the fat breakdown signal of epinephrine.

So anything that increases epinephrine will have sort of pound for pound or site for site visceral versus subcutaneous is going to have a better visceral response.

So the more the epinephrine is being targeted.

So that's going to be things like exercise and like cold therapy, for example, cold immersion.

Talk about an epinephrine spike.

So anytime you're really activating the sympathetic nervous system, you're going to be sort of

molecule for molecule, cell for cell, targeting the visceral more than the subcutaneous.

So it is more responsive to that sympathetic tone than subcutaneous fat is.

Great.

And I'm a big advocate of cold immersion.

Yeah, yeah.