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FoundMyFitness

#104 Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep

11 Jul 2025

Transcription

Full Episode

0.031 - 21.28 Dr. Rhonda Patrick

Insulin resistance is increasingly recognized as a key contributor to chronic diseases such as obesity, diabetes, cardiovascular disease, and even cognitive decline, often developing silently years before conventional tests detect a problem. Yet most people don't realize they're insulin resistant until blood glucose tests finally flash a warning sign, often decades too late.

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21.26 - 36.67 Dr. Rhonda Patrick

The reality is, is that millions of people are unknowingly walking around with persistently elevated insulin levels, what we might call pre-pre-diabetes. And this silent dysfunction has profound implications for their long-term metabolic health, disease risk, and longevity.

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36.65 - 56.97 Dr. Rhonda Patrick

Today, I'm joined by Dr. Ben Bickman, an expert in insulin metabolism and one of the most insightful voices in unraveling the complexities behind insulin resistance. Dr. Bickman is a professor of physiology and developmental biology at Brigham Young University, whose research has reshaped our understanding of insulin's broader roles far beyond glucose regulation.

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56.95 - 69.544 Dr. Rhonda Patrick

His work highlights how insulin resistance differentially impacts muscle, liver, and fat tissue, the critical roles environmental toxins play, and the practical interventions that can significantly restore insulin sensitivity.

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69.564 - 84.78 Dr. Rhonda Patrick

In this episode, Ben and I dive deep into crucial topics, including why insulin resistance remains hidden until advanced stages, how to detect it early through simple tests, and actionable first steps to reverse insulin resistance immediately.

84.76 - 94.792 Dr. Rhonda Patrick

what insulin's broader physiological roles are beyond just blood glucose, its profound influence on fat storage, appetite regulation, inflammation, and chronic disease.

95.112 - 114.075 Dr. Rhonda Patrick

We also discuss macronutrients and insulin sensitivity, discussing how different dietary compounds like refined carbohydrates, sugars, even certain types of fats like saturated fats and polyunsaturated fats uniquely impact insulin signaling, inflammation, and metabolic health, as well as their relative roles in driving insulin resistance.

114.055 - 124.431 Dr. Rhonda Patrick

We discuss how meal timing, frequency and caloric restriction independently influence insulin sensitivity, including practical insights into intermittent fasting and time-restricted eating protocols.

124.752 - 137.211 Dr. Rhonda Patrick

We also discuss why not all fat cells are equal, including the metabolic dangers of visceral fat versus subcutaneous fat, the concept of personalized fat threshold, and what actually happens to fat cells during weight loss.

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