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Dr. Ben Bikman

๐Ÿ‘ค Speaker
1894 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

You must, to put it in a succinct sort of thesis statement, you must have elevated insulin to signal the growth of fat cell, and you must have sufficient energy to fuel the growth of the fat cell. Either is insufficient. You need both. I simply harp more on the insulin because it's the one that's so much more readily overlooked.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

You must, to put it in a succinct sort of thesis statement, you must have elevated insulin to signal the growth of fat cell, and you must have sufficient energy to fuel the growth of the fat cell. Either is insufficient. You need both. I simply harp more on the insulin because it's the one that's so much more readily overlooked.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

The caloric-centric view of obesity has so enamored the world that there's almost no room intellectually to consider that there's another facet to this, namely hormones. But let me just revisit the role of the fat cell very briefly. And this is a particular interest with two guys like me and you. You have Ben Bickman, who is kind of European, Northern European descent. And I have Drew.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

The caloric-centric view of obesity has so enamored the world that there's almost no room intellectually to consider that there's another facet to this, namely hormones. But let me just revisit the role of the fat cell very briefly. And this is a particular interest with two guys like me and you. You have Ben Bickman, who is kind of European, Northern European descent. And I have Drew.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

The caloric-centric view of obesity has so enamored the world that there's almost no room intellectually to consider that there's another facet to this, namely hormones. But let me just revisit the role of the fat cell very briefly. And this is a particular interest with two guys like me and you. You have Ben Bickman, who is kind of European, Northern European descent. And I have Drew.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Drew, I think you're South Asian. Indian. Yep. So these are two remarkably comparable ethnicities. When I did my postdoctoral work in Singapore, one of the reasons Singapore was so interested in partnering with Duke University, which is where I was,

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Drew, I think you're South Asian. Indian. Yep. So these are two remarkably comparable ethnicities. When I did my postdoctoral work in Singapore, one of the reasons Singapore was so interested in partnering with Duke University, which is where I was,

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Drew, I think you're South Asian. Indian. Yep. So these are two remarkably comparable ethnicities. When I did my postdoctoral work in Singapore, one of the reasons Singapore was so interested in partnering with Duke University, which is where I was,

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

was to understand these ethnic differences on how you can take ethnicities, particularly in Singapore, with both Chinese, South Asian, Malaysian, and European, and you have these four different guys who are best drinking buddies and they're all gaining weight, and yet they start to suffer the consequences of that weight gain at very different rates.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

was to understand these ethnic differences on how you can take ethnicities, particularly in Singapore, with both Chinese, South Asian, Malaysian, and European, and you have these four different guys who are best drinking buddies and they're all gaining weight, and yet they start to suffer the consequences of that weight gain at very different rates.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

was to understand these ethnic differences on how you can take ethnicities, particularly in Singapore, with both Chinese, South Asian, Malaysian, and European, and you have these four different guys who are best drinking buddies and they're all gaining weight, and yet they start to suffer the consequences of that weight gain at very different rates.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

But a study done in Caucasians compared to South Asians, not only do we know that the average South Asian Indian has a fasted insulin that is more than double what his Caucasian counterpart is, but also, even at the same body weight, his fat cells are about three to four times larger than his Caucasian counterpart. And this could explain why partly India has more people with type 2 diabetes.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

But a study done in Caucasians compared to South Asians, not only do we know that the average South Asian Indian has a fasted insulin that is more than double what his Caucasian counterpart is, but also, even at the same body weight, his fat cells are about three to four times larger than his Caucasian counterpart. And this could explain why partly India has more people with type 2 diabetes.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

But a study done in Caucasians compared to South Asians, not only do we know that the average South Asian Indian has a fasted insulin that is more than double what his Caucasian counterpart is, but also, even at the same body weight, his fat cells are about three to four times larger than his Caucasian counterpart. And this could explain why partly India has more people with type 2 diabetes.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Absolute numbers more than anyone, but of course India's population is so massive. Even per capita, it's approaching the number one spot in the world, being truly the diabetes capital of the world. And a part of it is this combination, yes, environment, diet matters, but also genetics. And so it's very much important for us to understand what we could call the personal fat threshold.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Absolute numbers more than anyone, but of course India's population is so massive. Even per capita, it's approaching the number one spot in the world, being truly the diabetes capital of the world. And a part of it is this combination, yes, environment, diet matters, but also genetics. And so it's very much important for us to understand what we could call the personal fat threshold.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Absolute numbers more than anyone, but of course India's population is so massive. Even per capita, it's approaching the number one spot in the world, being truly the diabetes capital of the world. And a part of it is this combination, yes, environment, diet matters, but also genetics. And so it's very much important for us to understand what we could call the personal fat threshold.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

That based on our genetics and partly our diet, certain bodies have the potential to store fat in their fat cells to varying levels. And just Caucasians in the case of this example appear to have the higher threshold. But basically, as long as you can continue to store fat in fat cells, the body stays metabolically sound.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

That based on our genetics and partly our diet, certain bodies have the potential to store fat in their fat cells to varying levels. And just Caucasians in the case of this example appear to have the higher threshold. But basically, as long as you can continue to store fat in fat cells, the body stays metabolically sound.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

That based on our genetics and partly our diet, certain bodies have the potential to store fat in their fat cells to varying levels. And just Caucasians in the case of this example appear to have the higher threshold. But basically, as long as you can continue to store fat in fat cells, the body stays metabolically sound.